膀胱内注射肉毒杆菌毒素治疗特发性逼尿肌过度活动后出现的长期尿潴留。
Prolonged urinary retention after intravesical botulinum injection for treatment of idiopathic detrusor overactivity.
作者信息
King Ashley B, Rapp David E
机构信息
Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.
出版信息
Can J Urol. 2011 Apr;18(2):5657-9.
INTRODUCTION
Botulinum toxin (BTX) has emerged as a treatment of refractory overactive bladder (OAB) and, while well tolerated, there exists concern regarding postoperative urinary retention.
CASE
A 75-year-old female underwent intravesical BTX-A injection, which was followed by a prolonged episode of urinary retention, highlighting an unusual duration and degree of UR associated with BTX-A injection in the treatment of idiopathic detrusor overactivity (IDO). This case illustrates clinically significant urinary retention with bladder diaries demonstrating persistent postvoid residual (PVR) measurements exceeding voided volume until 9 month follow up.
CONCLUSIONS
Notably, this duration and severity of urinary retention remains rare. However, this case underscores the need to appropriately counsel patients regarding the risks associated with intravesical injection of BTX-A.
引言
肉毒杆菌毒素（BTX）已成为治疗难治性膀胱过度活动症（OAB）的一种方法，虽然耐受性良好，但人们对术后尿潴留仍存在担忧。
病例
一名75岁女性接受了膀胱内注射BTX-A治疗，随后出现了长时间的尿潴留，这突出了在治疗特发性逼尿肌过度活动症（IDO）时，与BTX-A注射相关的尿潴留的异常持续时间和程度。该病例显示出具有临床意义的尿潴留，膀胱日记表明，直到9个月的随访时，排尿后残余尿量（PVR）测量值持续超过排尿量。
结论
值得注意的是，这种尿潴留的持续时间和严重程度仍然罕见。然而，该病例强调了需要就膀胱内注射BTX-A相关的风险对患者进行适当的咨询。
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