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共聚焦显微镜在皮肤肿瘤学实践中的作用。

The role of confocal microscopy in the dermato-oncology practice.

作者信息

Diaconeasa A, Boda D, Neagu M, Constantin C, Căruntu C, Vlădău L, Guţu D

机构信息

Department of Dermatology, Gr. Alexandrescu Children's Hospital, Bucharest, Romania.

出版信息

J Med Life. 2011 Jan-Mar;4(1):63-74. Epub 2011 Feb 25.

Abstract

Reflectance-mode confocal microscopy (RCM) is a new in vivo skin imaging technique. We present our one-year experience in RCM examinations in skin tumors and the retrospective analysis of patients enrolled in the Dermatological Department of 'N. Paulescu' Institute using the Fotofinder Dermoscope IIŴ for the dermatoscopy analysis and VivaScope 1500Ŵ for in vivo RCM. We established the rank of RCM in the complex algorithm of skin cancer diagnose, showing that the presented experience can open new possibilities to implement this automated image analyzing system in the routine practice. Our analyzed cases clearly showed that confocal microscopy, therefore, optical biopsy, could guide the clinician towards an accurate diagnosis before surgical removal. Moreover, we emphasized that the development of this technique increases the potential of future teledermatologic applications.

摘要

反射式共聚焦显微镜(RCM)是一种新型的体内皮肤成像技术。我们介绍了我们在皮肤肿瘤RCM检查方面的一年经验,以及对“N. Paulescu”研究所皮肤科登记患者的回顾性分析,其中使用Fotofinder Dermoscope IIŴ进行皮肤镜分析,使用VivaScope 1500Ŵ进行体内RCM检查。我们确定了RCM在皮肤癌复杂诊断算法中的地位,表明所展示的经验可为在常规实践中实施这种自动图像分析系统开辟新的可能性。我们分析的病例清楚地表明,共聚焦显微镜检查,即光学活检,可在手术切除前指导临床医生做出准确诊断。此外,我们强调这项技术的发展增加了未来远程皮肤病学应用的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae04/3056424/20882611678f/JMedLife-04-63-g001.jpg

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