Dermatology Clinics, Ministry of Health, Adana Numune Education and Research Hospital, Seyhan Practice Center, Adana, Turkey.
Indian J Dermatol Venereol Leprol. 2011 May-Jun;77(3):294-9. doi: 10.4103/0378-6323.79698.
The management of women with chronic benign vulvar dermatoses has been one of the most difficult and challenging aspects of women's healthcare for a long time.
Our aim was to compare the ability to approach the specific diagnosis of nonneoplastic and noninfectious vulva diseases, between the new classification system and the old classification system.
One hundred women with chronic vulvar pruritus were included in the study. After detailed examination of the vulva, all visible lesions were biopsied, with normal skin included. All specimens was sent for dermatopathology and examined simultaneously under a binocular microscope by two pathologists. Specific diagnosis if possible and histopathological findings were classified according to both the 1987 and 2006 International Society for the Study of Vulvar Diseases (ISSVD) classifications. The ratios that were able to be approached on the specific diagnosis, with the aid the two classification systems, were compared.
Specific clinical diagnosis by both pathological and after using clinicopathological correlation was possible in 69 out of 91 patients (75.8%) according to the 1987 ISSVD classification, and in 81 out of 91 patients (89.0%) according to the ISSVD 2006 classification system. The difference in the clinical diagnosis ratios between the two classification systems was statistically significant ( P < 0.05). In a subgroup of women without specific diagnosis at the time of pathological examination, clinical diagnosis was made in 28 out of 50 women (56%) after using the clinicopathological correlation according to the ISSVD 1987 classification, whereas, specific diagnosis was made in 39 out of 49 (79.6%) women after using the clinicopathological correlation according to the ISSVD 2006 classification. The difference was statistically significant in terms of the ratio of the ability to achieve a specific diagnosis (P < 0.01).
ISSVD 2006 classification of nonneoplastic and noninfectious vulvar disease is more useful than the former classification, in terms of approaching the specific diagnosis of vulvar dermatoses.
长期以来，慢性良性外阴皮肤病的治疗一直是女性健康护理中最困难和最具挑战性的方面之一。
我们的目的是比较新分类系统和旧分类系统在非肿瘤性和非传染性外阴疾病的具体诊断方面的能力。
本研究纳入了 100 例慢性外阴瘙痒患者。在对外阴进行详细检查后，对所有可见病变进行活检，包括正常皮肤。所有标本均送往皮肤科，并由两位病理学家同时在双目显微镜下进行检查。尽可能进行具体诊断，并根据 1987 年和 2006 年国际外阴疾病研究学会（ISSVD）分类对组织病理学发现进行分类。比较两种分类系统辅助下具体诊断的可能性比例。
根据 1987 年 ISSVD 分类，91 例患者中 69 例（75.8%）通过病理和使用临床病理相关性可获得具体临床诊断，91 例患者中 81 例（89.0%）根据 ISSVD 2006 分类系统可获得具体临床诊断。两种分类系统的临床诊断比例差异有统计学意义（P<0.05）。在病理检查时没有具体诊断的女性亚组中，根据 1987 年 ISSVD 分类使用临床病理相关性后，50 例女性中有 28 例（56%）获得了具体诊断，而根据 2006 年 ISSVD 分类使用临床病理相关性后，49 例女性中有 39 例（79.6%）获得了具体诊断。在具体诊断能力的比值方面，差异具有统计学意义（P<0.01）。
ISSVD 2006 年非肿瘤性和非传染性外阴疾病分类在接近外阴皮肤病的具体诊断方面比旧分类更有用。
