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去表皮撕囊的自动化角膜内皮移植术后的深板层角膜移植。

Deep anterior lamellar keratoplasty after descemet stripping automated endothelial keratoplasty.

机构信息

Villa Serena Hospital, Department of Ophthalmology, Forlì, Italy.

出版信息

Cornea. 2011 Sep;30(9):1048-50. doi: 10.1097/ICO.0b013e318207ec97.

Abstract

PURPOSE

To report, using 2 illustrative cases, a new technique in which deep anterior lamellar keratoplasty (DALK) is performed after Descemet stripping automated endothelial keratoplasty (DSAEK) for cases of residual stromal opacity after the resolution of corneal endothelial failure.

METHOD

DSAEK was performed in 2 eyes with endothelial failure and stromal opacities of uncertain visual significance. After surgery, visual acuity failed to adequately improve. Residual stromal opacities were present in each case. Best-corrected visual acuity after DSAEK was 20/100 in case 1 and 20/200 in case 2. Subsequently, both cases underwent DALK.

RESULTS

Surgeries and postoperative courses were uneventful in each case. After DALK, best-corrected visual acuity improved to 20/30 (-1.0/-4.0 × 90 degrees) at 9 months in case 1 and remained stable during a total of 24 months. In case 2, best-corrected visual acuity increased to 20/40 at 6 months (+2.00/-6.00 × 40 degrees).

CONCLUSIONS

A new approach has been used to preserve the healthy DSAEK graft in these eyes with significant residual corneal opacities after the resolution of endothelial failure. Corneal clarity was reestablished by substituting the host central corneal stroma in its entire thickness with donor tissue, thus performing a DALK in addition to a DSAEK and avoiding a second intraocular surgery.

摘要

目的

通过 2 个实例报告一种新的技术,即对于角膜内皮功能失代偿消退后仍存在基质混浊、但混浊程度对视力影响不确定的病例,先施行撕囊后的去内皮角膜移植术(DSAEK),然后再行深板层角膜移植术(DALK)。

方法

对 2 例因内皮功能失代偿而导致角膜混浊、视力下降的患者施行 DSAEK 手术。术后视力恢复欠佳,角膜混浊仍存在。DSAEK 术后最佳矫正视力在病例 1 中为 20/100,在病例 2 中为 20/200。随后,这 2 例患者均接受了 DALK 手术。

结果

这 2 例患者的手术及术后过程均顺利。DALK 术后 9 个月,病例 1 的最佳矫正视力提高至 20/30(-1.0/-4.0 × 90 度),随访 24 个月,视力保持稳定。病例 2 的最佳矫正视力在术后 6 个月时提高至 20/40(+2.00/-6.00 × 40 度)。

结论

在角膜内皮功能失代偿消退后,对于存在明显残余角膜混浊、但混浊程度对视力影响不确定的病例,本研究采用了一种新的方法,即在 DSAEK 手术的基础上联合 DALK,保留健康的 DSAEK 移植物,即用供体组织置换宿主中央角膜全层,从而恢复角膜透明性,避免了二次眼内手术。

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