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颈动脉支架的径向力测量:支架设计和病变长度的影响。

Radial force measurements in carotid stents: influence of stent design and length of the lesion.

机构信息

Department of Vascular Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

出版信息

J Vasc Interv Radiol. 2011 May;22(5):661-6. doi: 10.1016/j.jvir.2011.01.450.

DOI:10.1016/j.jvir.2011.01.450
PMID:21514520
Abstract

PURPOSE

To assess the differences in radial force of carotid stents and whether the length of the lesion influences the measurements.

MATERIALS AND METHODS

Different models of tapered stents of similar size (length, 30 mm) were used. The tapered nitinol Acculink, Protégé, and Cristallo Ideale carotid artery stents and the straight, braided Elgiloy carotid Wallstent were compared. A measurement device consisting of three film loops along the stent body connected to aluminium rods with copper strain gauges was developed. Five stents of each type were deployed within 3-mm stenoses in simulated long (26 mm) and short (8 mm) stenoses.

RESULTS

In the short stenosis simulation, the greatest radial force was seen in the Protégé stent, at 3.14 N ± 0.45, followed by the Cristallo Ideale stent (1.73 N ± 0.51), Acculink (1.16 N ± 0.21), and Wallstent (0.84 N ± 0.10; P < .001). In the long stenosis simulation, peak radial force again was highest in the Protégé stent (1.67 N ± 0.37), but the Acculink stent was second (0.95 N ± 0.12) and the Wallstent third (0.80 N ± 0.06). The Cristallo Ideale stent, in contrast to the short stenosis simulation, produced the least radial force (0.44 N ± 0.13) in the long stenosis simulation (P = .001).

CONCLUSIONS

Radial forces exerted by carotid stents vary significantly among stent designs. Differences between stent types are dependent on the length of the stenosis. An understanding of radial force is necessary for a well-considered choice of stent type in each individual patient.

摘要

目的

评估颈动脉支架的径向力差异,以及病变长度是否会影响测量结果。

材料与方法

使用了不同型号、尺寸相近(长度 30mm)的锥形支架。对比了锥形镍钛合金 Acculink、Protégé 和 Cristallo Ideale 颈动脉支架,以及直形编织 Elgiloy 颈动脉 Wallstent。开发了一种由三个沿支架体的胶片环组成的测量装置,这些胶片环连接到带有铜应变片的铝棒上。将每种类型的 5 个支架分别放置在模拟的长(26mm)和短(8mm)狭窄处的 3mm 狭窄处。

结果

在短狭窄模拟中,Protégé 支架产生的最大径向力为 3.14N±0.45N,其次是 Cristallo Ideale 支架(1.73N±0.51N)、Acculink 支架(1.16N±0.21N)和 Wallstent 支架(0.84N±0.10N;P<0.001)。在长狭窄模拟中,峰值径向力再次以 Protégé 支架最高(1.67N±0.37N),但 Acculink 支架次之(0.95N±0.12N),Wallstent 支架第三(0.80N±0.06N)。与短狭窄模拟相反,Cristallo Ideale 支架在长狭窄模拟中产生的径向力最小(0.44N±0.13N)(P=0.001)。

结论

颈动脉支架的径向力在支架设计之间存在显著差异。支架类型之间的差异取决于狭窄的长度。了解径向力对于在每个患者中进行仔细考虑的支架类型选择是必要的。

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