Departamento de Genética, Programa de Pós-Graduação em Genética e Biologia Molecular, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Am J Phys Anthropol. 2011 Jul;145(3):371-81. doi: 10.1002/ajpa.21505. Epub 2011 Apr 25.
Information on one Ecuadorian and three Peruvian Amerindian populations for 11 autosomal short tandem repeat (STR) loci is presented and incorporated in analyses that includes 26 other Native groups spread all over South America. Although in comparison with other studies we used a reduced number of markers, the number of populations included in our analyses is currently unmatched by any genome-wide dataset. The genetic polymorphisms indicate a clear division of the populations into three broad geographical areas: Andes, Amazonia, and the Southeast, which includes the Chaco and southern Brazil. The data also show good agreement with proposed hypotheses of splitting and dispersion of major language groups over the last 3,000 years. Therefore, relevant aspects of Native American history can be traced using as few as 11 STR autosomal markers coupled with a broad geographic distribution of sampled populations.
提供了一份关于厄瓜多尔和秘鲁的三个美洲印第安人群体的 11 个常染色体短串联重复（STR）基因座的信息，并将其纳入包括分布在南美洲各地的 26 个其他本土群体的分析中。尽管与其他研究相比，我们使用的标记物数量较少，但我们分析中包含的群体数量目前在任何全基因组数据集中都无法比拟。遗传多态性表明，这些群体明显分为三个主要的地理区域：安第斯山脉、亚马逊地区和东南部，包括查科地区和巴西南部。这些数据还与过去 3000 年来主要语言群体分裂和扩散的假设非常吻合。因此，使用尽可能少的 11 个常染色体 STR 标记物和广泛的样本群体地理分布，就可以追踪到美洲原住民历史的相关方面。
