15 个 STR 在中国代表性人群样本中的等位基因频率。
Allele frequencies of 15 STRs in a representative sample of the Brazilian population.
机构信息
Laboratório Alvaro, Centro de Análises e Pesquisas Clínicas, Rua General Osório, 3212, Bairro Centro, Cascavel, Paraná, Brazil.
出版信息
Forensic Sci Int Genet. 2010 Feb;4(2):e61-3. doi: 10.1016/j.fsigen.2009.05.006. Epub 2009 Jun 16.
Allele frequencies for 15 short tandem repeat (STR) loci were obtained from a sample of 12,030 individuals undergoing paternity testing. This sample includes individuals from all States in Brazil, combined according to the current country division into five regions (North, Northeast, Central West, Southeast, and South). The most polymorphic loci were D2S1338 and D18S51. All the analysed loci meet Hardy-Weinberg equilibrium expectations. Combined power of discrimination and combined power of exclusion for the 15 tested STR loci were 0.999999999999990 and 0.9999992, respectively. Comparative analysis between populations from different Brazilian macroregions as well as between Brazil and other relevant populations are presented.
从 12030 名进行亲子鉴定的个体中获得了 15 个短串联重复（STR）基因座的等位基因频率。该样本包括来自巴西所有州的个体，根据当前国家划分组合成五个地区（北部、东北部、中西部、东南部和南部）。多态性最高的基因座是 D2S1338 和 D18S51。所有分析的基因座均符合哈迪-温伯格平衡预期。15 个测试 STR 基因座的联合鉴别力和联合排除力分别为 0.999999999999990 和 0.9999992。呈现了不同巴西大地区人群之间以及巴西与其他相关人群之间的比较分析。
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