Suppr超能文献

对吉隆坡大学医院31名易出现瘀伤的患者进行的一项研究。

A study of 31 patients with easy bruising from University Hospital, Kuala Lumpur.

作者信息

Chin N S, Koong P L

机构信息

Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur.

出版信息

Med J Malaysia. 1990 Dec;45(4):325-8.

PMID:2152054
Abstract

Thirty one patients were investigated for the main complaint of easy bruising. These patients had normal platelet count with no past history of immune thrombocytopenia or systemic disorders known to predispose to bruising and a negative drug history. The evaluation of these patients included clinical review (history and physical examination) plus coagulation tests consisting of bleeding time, prothrombin time, partial thromboplastin time, thrombin time, fibrinogen level, FXIII screen and platelet functions test. Seven of the paediatric patients had acquired platelet dysfunction with eosinophilia (APDE). In 17 (94.4%) of the 18 adult patients no abnormality was demonstrated. Hence APDE was the commonest cause of easy bruising in children while the haemostatic defect contributing to easy bruising in adults remained unknown.

摘要

对31例以易出现瘀斑为主诉的患者进行了调查。这些患者血小板计数正常,既往无免疫性血小板减少症病史或已知易导致瘀斑的全身性疾病史,且药物史阴性。对这些患者的评估包括临床检查(病史和体格检查)以及凝血试验,凝血试验包括出血时间、凝血酶原时间、部分凝血活酶时间、凝血酶时间、纤维蛋白原水平、FXIII筛查和血小板功能试验。7例儿科患者患有获得性血小板功能障碍伴嗜酸性粒细胞增多症(APDE)。18例成年患者中有17例(94.4%)未发现异常。因此,APDE是儿童易出现瘀斑的最常见原因,而导致成人易出现瘀斑的止血缺陷仍不清楚。

相似文献

2
Bruising and bleeding in infants and children--a practical approach.
Br J Haematol. 2006 May;133(3):221-31. doi: 10.1111/j.1365-2141.2006.06016.x.
4
Bleeding and bruising: a diagnostic work-up.
Am Fam Physician. 2008 Apr 15;77(8):1117-24.
5
The spectrum of inherited bleeding disorders in pediatrics.
Blood Coagul Fibrinolysis. 2008 Dec;19(8):771-5. doi: 10.1097/MBC.0b013e32830f1b99.
7
A 20-year-old man with eosinophilia and easy bruisability.
Singapore Med J. 1999 Oct;40(10):652-3.
8
Acquired platelet dysfunction with eosinophilia in children in the south of Thailand.
Platelets. 2001 Feb;12(1):5-14. doi: 10.1080/09537100020031180.
9
Laboratory evaluation of platelet dysfunction.
Clin Lab Med. 1995 Mar;15(1):1-38.
10
Evaluation of mild bleeding disorders and easy bruising.
Blood Rev. 1994 Jun;8(2):98-104. doi: 10.1016/s0268-960x(05)80014-1.

引用本文的文献

1
Eosinophil Granulocyte and NK Cell-Mediated Platelet Destruction in Immune Thrombocytopenia.
Indian J Hematol Blood Transfus. 2018 Jan;34(1):121-124. doi: 10.1007/s12288-017-0830-z. Epub 2017 May 17.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验