Department of Pediatrics, Hillerød Hospital, Hillerød, Denmark.
Clin Endocrinol (Oxf). 2011 Jun;74(6):756-61. doi: 10.1111/j.1365-2265.2011.03995.x.
To determine uterine and ovarian size in Turner syndrome (TS) and to compare uterine and ovarian size evaluated by transabdominal ultrasound (US) and magnetic resonance imaging (MRI) in girls with TS and two groups of controls.
A cross-sectional study.
Forty-one girls with TS (17·0 ± 3·3 years, range 11·2-24·9 years), 50 healthy age-matched controls (16·9 ± 3·2 years, range 12·5-25·0 years) and 107 Tanner-stage-matched controls (15·0 ± 3·2 years, range 10·1-24·2).
Uterine and ovarian volume by US and MRI.
Ovaries were detected in 37% in TS by US and in 55% in TS by MRI (P = 0·1). Total ovarian volume was lower in TS compared to both groups of controls (TS vs C-US: median 1·1 ml (range 0·1-29·3) vs 11·52 ml (1·9-77·9), P = 0·001, TS vs C-MRI: 1·0 ml (0·1-34·2) vs 13·2 ml (2·4-30·1), P < 0·0005). Mean difference in total ovarian volume measured by MRI and US in patients with TS was 2·3 ± 3·8 ml (P = 0·01). Mean uterine volume by MRI was lower in TS compared to controls (29·5 ± 25·1 vs 54·3 ± 23·3 ml, P < 0·0005). Uterine volume by US was lower in TS at Tanner stage B5 compared to controls (TS vs C: 33·6 ± 18·2 vs 50·2 ± 18·0 ml, P = 0·007).
A larger ovarian volume was detected by MRI in TS compared to US. This finding is important with the advancements of performing ovarian biopsies for cryopreservation and later reimplantation. Mean uterine volumes by MRI and US in fully matured TS were lower compared to controls despite appropriate hormonal replacement therapy in TS.
确定特纳综合征（TS）患者的子宫和卵巢大小，并比较经腹超声（US）和磁共振成像（MRI）评估的 TS 患者与两组对照组的子宫和卵巢大小。
横断面研究。
41 名 TS 女孩（17.0 ± 3.3 岁，范围 11.2-24.9 岁），50 名年龄匹配的健康对照组（16.9 ± 3.2 岁，范围 12.5-25.0 岁）和 107 名 Tanner 分期匹配的对照组（15.0 ± 3.2 岁，范围 10.1-24.2 岁）。
US 和 MRI 测量子宫和卵巢体积。
US 检测到 37%的 TS 患者有卵巢，MRI 检测到 55%的 TS 患者有卵巢（P = 0.1）。与两组对照组相比，TS 患者的总卵巢体积较低（TS 与 C-US：中位数 1.1 ml（范围 0.1-29.3）与 11.52 ml（1.9-77.9），P = 0.001，TS 与 C-MRI：1.0 ml（0.1-34.2）与 13.2 ml（2.4-30.1），P < 0.0005）。MRI 和 US 测量的 TS 患者总卵巢体积的平均差异为 2.3 ± 3.8 ml（P = 0.01）。与对照组相比，TS 患者的 MRI 测量的子宫体积较小（29.5 ± 25.1 与 54.3 ± 23.3 ml，P < 0.0005）。与对照组相比，TS 患者在 Tanner 分期 B5 时的 US 测量的子宫体积较小（TS 与 C：33.6 ± 18.2 与 50.2 ± 18.0 ml，P = 0.007）。
与 US 相比，MRI 检测到 TS 患者的卵巢体积更大。这一发现对于进行卵巢活检以进行冷冻保存和随后的再植入具有重要意义。尽管 TS 患者接受了适当的激素替代治疗，但 MRI 和 US 测量的完全成熟的 TS 患者的平均子宫体积仍低于对照组。
