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[智利首个地区的恰加斯心肌病。临床、流行病学和寄生虫学研究]

[Chagas cardiopathy in the first region of Chile. Clinical, epidemiologic, and parasitologic study].

作者信息

Arribada A, Apt W, Aguilera X, Solari A, Arribada A, Sandoval J

机构信息

Departamento de Medicina, Facultad de Medicina, Universidad de Chile.

出版信息

Rev Med Chil. 1990 Aug;118(8):846-54.

PMID:2152227
Abstract

705 inhabitants of rural towns in northern Chile were surveyed to study chagasic infection and cardiac involvement. Clinical evaluation, electrocardiogram, indirect hemagglutination test and xenodiagnosis for reactors were employed. Culture of positive xenodiagnosis was done to identify different zymodemes and schizodemes of T cruzi, T spinolai was not found in this area implying the absence of a wild cycle. Triotomines were not found over 3000 m high. Four cases of Z2b T cruzi strains were found. Simultaneous infection by Z1 and Z2b strains was found in the same bug obtained from houses. Overall human infection rate was 10%, and 69% of them showed altered electrocardiograms. Therefore, a lower infection rate but greater evidence of cardiac involvement is found in northern Chile compared to other areas in the country.

摘要

对智利北部乡村城镇的705名居民进行了调查,以研究恰加斯病感染和心脏受累情况。采用了临床评估、心电图、间接血凝试验以及对反应者进行异种接种诊断。对阳性异种接种诊断结果进行培养,以鉴定克氏锥虫的不同酶谱型和裂殖体型,该地区未发现斯氏锥虫,这意味着不存在野生传播循环。在海拔3000米以上未发现锥蝽。发现了4例Z2b克氏锥虫菌株。从房屋采集的同一只锥蝽体内发现了Z1和Z2b菌株的同时感染。总体人群感染率为10%,其中69%的人心电图异常。因此,与该国其他地区相比,智利北部的感染率较低,但心脏受累的证据更为明显。

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