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1-（2-苯甲酰基-1-苯基-乙基）-4- [（2-羟基-1-萘基）亚甲基氨基]-3-苯基-1H-1,2,4-三唑-5（4H）-硫酮

1-(2-Benzoyl-1-phenyl-eth-yl)-4-[(2-hy-droxy-1-naphth-yl)methyl-idene-amino]-3-phenyl-1H-1,2,4-triazole-5(4H)-thione.

作者信息

Wang Wei, Yao Hong-Guo, Gao Yan, Zhang Jing-Jing, Jia Xiao-Yu

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Feb 19;67(Pt 3):o675. doi: 10.1107/S1600536811005721.

DOI:10.1107/S1600536811005721
PMID:21522423
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3051956/
Abstract

In the title mol-ecule, C(34)H(26)N(4)O(2)S, the hy-droxy group is involved in an intra-molecular O-H⋯N hydrogen bond. The naphthyl ring system and the central triazole ring form a dihedral angle of 37.8 (1)°. The crystal packing exhibits weak inter-molecular C-H⋯O and C-H⋯π inter-actions.

摘要

在标题分子C(34)H(26)N(4)O(2)S中，羟基参与了分子内的O-H⋯N氢键。萘环系统与中心三唑环形成的二面角为37.8 (1)°。晶体堆积呈现出弱的分子间C-H⋯O和C-H⋯π相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9b/3051956/f6fc83351437/e-67-0o675-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9b/3051956/f6fc83351437/e-67-0o675-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9b/3051956/f6fc83351437/e-67-0o675-fig1.jpg

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本文引用的文献

1
1-(2-Benzoyl-1-phenyl-eth-yl)-4-[(2-hy-droxy-1-naphth-yl)methyl-idene-amino]-3-methyl-1H-1,2,4-triazole-5(4H)-thione.1-（2-苯甲酰基-1-苯基-乙基）-4- [（2-羟基-1-萘基）亚甲基氨基]-3-甲基-1H-1,2,4-三唑-5（4H）-硫酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 8;67(Pt 2):o269. doi: 10.1107/S1600536810052979.
2
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
3
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Bioorg Med Chem. 2005 Nov 1;13(21):5921-6. doi: 10.1016/j.bmc.2005.07.031.
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In vitro study of some medicinally important Mannich bases derived from antitubercular agent.源自抗结核药物的一些具有重要药用价值的曼尼希碱的体外研究。
Bioorg Med Chem. 2004 Feb 1;12(3):571-6. doi: 10.1016/j.bmc.2003.11.001.
5
Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles.一些源自1,2,4-三唑的曼尼希碱的合成、表征及抗癌活性研究
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