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2-（4-氟苯基）-4-（4-甲氧基苯基）-5-（哌啶-1-基甲基）噻唑

2-(4-Fluoro-phen-yl)-4-(4-meth-oxy-phen-yl)-5-(piperidin-1-ylmeth-yl)thia-zole.

作者信息

Guo Chang-Bin, Lv Chao, Wei Wei, Zhou Hua

机构信息

Department of Chemistry, Capital Normal University, Beijing 100048, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 12;67(Pt 2):o361. doi: 10.1107/S1600536810054103.

DOI:10.1107/S1600536810054103
PMID:21523040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3051797/
Abstract

In the title compound, C(22)H(23)FN(2)OS, the piperidine ring shows chair confirmation and the two benzene rings make a dihedral angle of 17.0 (6)°. The thia-zole fragment is essentially planar with an r.m.s. deviation of 0.004 (2) Å and a maximum deviation of 0.006 (2) Å.. In the crystal, inter-molecular C-H⋯π inter-actions lead to the formation of a layer structure.

摘要

在标题化合物C₂₂H₂₃FN₂OS中，哌啶环呈椅式构象，两个苯环形成的二面角为17.0 (6)°。噻唑片段基本呈平面状，均方根偏差为0.004 (2) Å，最大偏差为0.006 (2) Å。在晶体中，分子间C-H⋯π相互作用导致形成层状结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cce/3051797/307af68768bb/e-67-0o361-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cce/3051797/fef6c2ecc168/e-67-0o361-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cce/3051797/307af68768bb/e-67-0o361-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cce/3051797/fef6c2ecc168/e-67-0o361-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cce/3051797/307af68768bb/e-67-0o361-fig2.jpg

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