Department of Periodontology, Academic Centre for Dentistry Amsterdam, University of Amsterdam, The Netherlands.
Caries Res. 2011;45(2):162-73. doi: 10.1159/000327374. Epub 2011 Apr 27.
The aim of this study was to systematically review the present literature on the effect of chlorhexidine varnish (CHX-V) on root caries.
The MEDLINE-PubMed, the Cochrane-CENTRAL and EMBASE databases were searched through December 2010 to identify any appropriate studies. Root caries incidence and root caries activity were selected as outcome variables.
An independent screening of the unique titles and abstracts of 24 MEDLINE-PubMed, 14 Cochrane-CENTRAL and 18 EMBASE papers resulted in 6 publications that met the eligibility criteria. Data extraction provided no conclusive evidence that the application of CHX-V is effective in patients when regular professional oral prophylaxis is performed. If effective, the 40% CHX-V was found to provide a benefit over a control or fluoride varnish. CHX-V at lower concentrations (1 and 10%) may provide protection against root caries in high-risk patients (such as geriatric and xerostomia patients) in the absence of regular professional oral prophylaxis.
Within the limitations of this review, it may be concluded that in the absence of regular professional tooth cleaning and oral hygiene instructions, CHX-V may provide a beneficial effect in patients in need of special care. The strength of this recommendation is graded as 'weak'.
本研究旨在系统回顾目前关于洗必泰涂料（CHX-V）对根面龋影响的文献。
通过检索 MEDLINE-PubMed、Cochrane-CENTRAL 和 EMBASE 数据库，截至 2010 年 12 月，查找相关研究。以根面龋发生率和根面龋活动度为观察指标。
通过对 24 篇 MEDLINE-PubMed、14 篇 Cochrane-CENTRAL 和 18 篇 EMBASE 论文的标题和摘要进行独立筛选，有 6 篇符合入选标准。数据分析没有明确证据表明，在进行常规专业口腔防护时，CHX-V 的应用对患者有效。如果有效，40%的 CHX-V 比对照组或氟化物涂料更有优势。在没有常规专业口腔防护的情况下，浓度较低的 CHX-V（1%和 10%）可能对高危患者（如老年和口干症患者）的根面龋有保护作用。
受本综述限制，在没有常规专业牙齿清洁和口腔卫生指导的情况下，CHX-V 可能对需要特殊护理的患者有有益的作用。这一推荐的强度等级为“弱”。
