Zhelnov V V, Andreeva N V, Shcheglova Iu M, Komarova I S, Dvoretskiĭ L I
Kardiologiia. 2010;50(11):12-6.
We have studied alterations of mitral valve geometry and quantitative parameters of mitral regurgitation in 130 patients with acute myocardial infarction in acute and subacute stages of the disease. Quantitative data of mitral regurgitation have been assessed using two quantitative Doppler techniques--proximal isovelocity surface area method (PISA-method) and quantitative Doppler technique (Q-DE-method). As a result of the research we have received data showing that in patients with acute myocardial infarction and ischemic mitral regurgitation mitral valve remodeling occurs with deformation of mitral structures inducing mitral regurgitation. We have observed correlation between degree of ischemic mitral regurgitation and structural valve alteration in patients with acute myocardial infarction.
我们研究了130例急性心肌梗死患者在疾病急性期和亚急性期二尖瓣几何形态的改变以及二尖瓣反流的定量参数。二尖瓣反流的定量数据采用两种定量多普勒技术进行评估——近端等速表面积法（PISA法）和定量多普勒技术（Q-DE法）。研究结果显示，在急性心肌梗死合并缺血性二尖瓣反流的患者中，二尖瓣结构变形导致二尖瓣反流，进而发生二尖瓣重塑。我们观察到急性心肌梗死患者缺血性二尖瓣反流程度与瓣膜结构改变之间存在相关性。
