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克罗地亚注射吸毒者中的丙型肝炎病毒抗体状况、社会人口学特征及风险行为。

Hepatitis C virus antibody status, sociodemographic characteristics, and risk behaviour among injecting drug users in Croatia.

作者信息

Cavlek Tatjana Vilibić, Marić Jelena, Katicić Ljiljana, Kolarić Branko

机构信息

Department of Virology, Croatian National Institute of Public Health, Zagreb, Croatia.

出版信息

Cent Eur J Public Health. 2011 Mar;19(1):26-9. doi: 10.21101/cejph.a3602.

Abstract

The study was conducted among 76 injecting drug users (IDU) from seven Croatian cities during a three-year period (2005-2007). Each participant completed a questionnaire on sociodemographic characteristics and potential risk factors for hepatitis C virurs (HCV) infection followed by anti-HCV and anti-HIV antibody testing. The mean patient age was 30. The majority of patients (69.8%) reported more than one potential exposure to HCV: 97.1% had shared injecting equipment, 75% reported risk sexual behaviour, and 56.3% reported a history of travelling abroad. The overall HCV seroprevalence was 51.3% (95% CI = 40-63%). HCV seroprevalence increased with increasing number of risk behaviours (p = 0.026). Needle sharing frequency was the most important risk factor for hepatitis C. The HCV seroprevalence rate ranged from 27.3% in IDUs who answered that they shared needles occasionally to 100% in IDUs who always shared needles (p < 0.001). No other risk factors (age, gender, educational level, marital and employment status, history of travelling abroad and sexual risk behaviour) were associated with HCV seropositivity.

摘要

该研究在三年期间(2005 - 2007年)对来自克罗地亚七个城市的76名注射吸毒者进行。每位参与者完成了一份关于社会人口学特征和丙型肝炎病毒(HCV)感染潜在危险因素的问卷,随后进行了抗HCV和抗HIV抗体检测。患者的平均年龄为30岁。大多数患者(69.8%)报告有不止一次潜在的HCV暴露:97.1%的人共用注射设备,75%的人报告有危险性行为,56.3%的人报告有出国旅行史。HCV总体血清阳性率为51.3%(95%置信区间 = 40 - 63%)。HCV血清阳性率随着危险行为数量的增加而升高(p = 0.026)。共用针头频率是丙型肝炎最重要的危险因素。HCV血清阳性率在偶尔共用针头的注射吸毒者中为27.3%,在总是共用针头的注射吸毒者中为100%(p < 0.001)。没有其他危险因素(年龄、性别、教育水平、婚姻和就业状况、出国旅行史和性危险行为)与HCV血清阳性相关。

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