Cavlek Tatjana Vilibić, Marić Jelena, Katicić Ljiljana, Kolarić Branko
Department of Virology, Croatian National Institute of Public Health, Zagreb, Croatia.
Cent Eur J Public Health. 2011 Mar;19(1):26-9. doi: 10.21101/cejph.a3602.
The study was conducted among 76 injecting drug users (IDU) from seven Croatian cities during a three-year period (2005-2007). Each participant completed a questionnaire on sociodemographic characteristics and potential risk factors for hepatitis C virurs (HCV) infection followed by anti-HCV and anti-HIV antibody testing. The mean patient age was 30. The majority of patients (69.8%) reported more than one potential exposure to HCV: 97.1% had shared injecting equipment, 75% reported risk sexual behaviour, and 56.3% reported a history of travelling abroad. The overall HCV seroprevalence was 51.3% (95% CI = 40-63%). HCV seroprevalence increased with increasing number of risk behaviours (p = 0.026). Needle sharing frequency was the most important risk factor for hepatitis C. The HCV seroprevalence rate ranged from 27.3% in IDUs who answered that they shared needles occasionally to 100% in IDUs who always shared needles (p < 0.001). No other risk factors (age, gender, educational level, marital and employment status, history of travelling abroad and sexual risk behaviour) were associated with HCV seropositivity.
该研究在三年期间(2005 - 2007年)对来自克罗地亚七个城市的76名注射吸毒者进行。每位参与者完成了一份关于社会人口学特征和丙型肝炎病毒(HCV)感染潜在危险因素的问卷,随后进行了抗HCV和抗HIV抗体检测。患者的平均年龄为30岁。大多数患者(69.8%)报告有不止一次潜在的HCV暴露:97.1%的人共用注射设备,75%的人报告有危险性行为,56.3%的人报告有出国旅行史。HCV总体血清阳性率为51.3%(95%置信区间 = 40 - 63%)。HCV血清阳性率随着危险行为数量的增加而升高(p = 0.026)。共用针头频率是丙型肝炎最重要的危险因素。HCV血清阳性率在偶尔共用针头的注射吸毒者中为27.3%,在总是共用针头的注射吸毒者中为100%(p < 0.001)。没有其他危险因素(年龄、性别、教育水平、婚姻和就业状况、出国旅行史和性危险行为)与HCV血清阳性相关。