Shadman Niloofar, Ebrahimi Shahram Farzin, Jafari Shahin, Eslami Mohammad
Assistant professor, Department of Restorative Dentistry, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.
Dent Res J (Isfahan). 2009 Spring;6(1):47-50.
Peripheral giant cell granuloma is one of the reactive hyperplastic lesions of the oral cavity, which originates from the periosteum or periodontal membrane following local irritation or chronic trauma. The purpose of this study was to present the clinical characteristics of peripheral giant cell granuloma in a group of Iranian population.
A series of 123 consecutive confirmed cases of peripheral giant cell granuloma after biopsy were evaluated. Age, sex, anatomic location, consistency, etiologic factor, pain and bleeding history, color, surface texture, and pedicle situation were recorded and were analyzed by chi-square test and values were considered to be significant if P < 0.05.
Age ranged from 6 to 75 years (mean 33 years). Women affected more than men (M/F 1:1.1). Peripheral giant cell granuloma was seen in the mandible more than in the maxilla and in the anterior region more than in the posterior region. In most cases, lesions were pink, pedunculated and had non-ulcerated surface. In less than half of the cases, there was no history of bleeding and also pain was rarely reported. Calculus was the most common etiologic factor.
The results confirmed that the clinical features of peripheral giant cell granuloma in a group of Iranian population are almost similar to those reported by other investigators.
外周性巨细胞肉芽肿是口腔的反应性增生性病变之一，其起源于局部刺激或慢性创伤后的骨膜或牙周膜。本研究的目的是呈现一组伊朗人群中外周性巨细胞肉芽肿的临床特征。
对一系列123例经活检确诊的外周性巨细胞肉芽肿连续病例进行评估。记录年龄、性别、解剖位置、质地、病因、疼痛和出血史、颜色、表面质地和蒂部情况，并通过卡方检验进行分析，若P < 0.05，则认为差异具有统计学意义。
年龄范围为6至75岁（平均33岁）。女性受累多于男性（男/女为1:1.1）。外周性巨细胞肉芽肿在下颌骨比在上颌骨更常见，在前部区域比在后部区域更常见。在大多数情况下，病变为粉红色、有蒂且表面无溃疡。不到一半的病例有出血史，疼痛也很少被报告。牙结石是最常见的病因。
结果证实，一组伊朗人群中外周性巨细胞肉芽肿的临床特征与其他研究者报告的特征几乎相似。
