Mora A, Brémond-Gignac D, Jany B, Sevestre H, Milazzo S
Service d'ophtalmologie, centre Saint-Victor, clinique ophtalmologique Saint-Victor, CHU d'Amiens, université Picardie Jules-Verne, 354, boulevard de Beauvillé, 80054 Amiens cedex 1, France.
J Fr Ophtalmol. 2011 May;34(5):303-8. doi: 10.1016/j.jfo.2010.11.022. Epub 2011 May 4.
A rare lesion of secondary amyloidosis of the cornea caused by trichiasis is reported. A 33-year-old Asian woman presented with progressive decrease of visual acuity of the right eye evolving over several years, combined with the growth of a lower budding, gelatinous, pink corneal mass located next to an inferior lid trichiasis. The treatment consisted of eyelid surgery for trichiasis, followed by ablation of the corneal lesion by anterior keratectomy. After 14 months of follow-up, no recurrence was observed. Visual acuity is 9/10 P3 without correction. Pathological examination of the mass revealed secondary corneal amyloidosis, AL type (light chains), rarely reported in the literature (18 cases). No other organ involvement by amyloidosis was identified. Corneal amyloidosis is a rare complication of trichiasis. To avoid recurrence, this anomaly should be recognized as the cause and should be treated prior to removal of the corneal lesion.
报告了一例由睑内翻引起的罕见的继发性角膜淀粉样变性病变。一名33岁的亚洲女性，右眼视力在数年中逐渐下降，同时下睑睑内翻旁出现一个生长的、胶冻状、粉红色的角膜肿物。治疗包括针对睑内翻的眼睑手术，随后通过前板层角膜切除术切除角膜病变。随访14个月后，未见复发。未矫正视力为9/10 P3。肿物的病理检查显示为继发性角膜淀粉样变性，AL型（轻链），文献中鲜有报道（18例）。未发现淀粉样变性累及其他器官。角膜淀粉样变性是睑内翻的一种罕见并发症。为避免复发，应将此异常视为病因，并在切除角膜病变之前进行治疗。
