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[与核医学中常规多模态检查相关的有效剂量]

[Effective doses associated to the usual multimodal examinations in nuclear medicine].

作者信息

Camacho López C, Martí Vidal J F, Falgás Lacueva M, Vercher Conejero J L

机构信息

Sección de Radiofísica, Servicio de Medicina Nuclear, Hospital Universitario La Fe, Valencia, España.

出版信息

Rev Esp Med Nucl. 2011 Sep-Oct;30(5):276-85. doi: 10.1016/j.remn.2011.02.008. Epub 2011 May 4.

DOI:10.1016/j.remn.2011.02.008
PMID:21531484
Abstract

OBJECTIVE

To know the effective doses (E) that can be given in the common multimodal procedures in nuclear medicine, Single Photon Emission Tomography and Positron Emission Tomography, combined with Computed Tomography, SPECT/CT and PET/CT. Effective dose will be expressed according to Background Equivalent Radiation Time (BERT) and the contribution of the CT scan to the total dose will also be studied.

MATERIAL AND METHODS

The effective dose of each procedure has been calculated as the sum of the external radiation dose (CT part) and internal one (radiopharmaceutical administration). Data from each side were collected through extensive literature search.

RESULTS

A range of minimum and maximum effective dose [E(min), E(max)] associated with each procedure is shown. These doses range from 0.5 to 49.1 mSv. BERT ranges from 2.6 months to 20.4 years. The CT contribution to the total effective dose varies from 2.1% to 93%, according to the image acquisition protocol and its purpose. Performing a diagnostic CT scan increases the dose up to a factor of 4.3 times compared to the dose used for CT acquisition for attenuation correction and anatomic localization.

CONCLUSIONS

This article focus on the effective dose level that can be given in multimodal procedures, bearing in mind that the data are subject to constant changes and should be updated periodically. It is important to know the dosimetric impact when the CT scan is added. The application of optimized protocols according to the indication of the study reduces the patient's exposure without the loss of significant information.

摘要

目的

了解在核医学常见的多模态检查程序中,即单光子发射计算机断层扫描(SPECT)和正电子发射断层扫描(PET)与计算机断层扫描(CT)相结合的SPECT/CT和PET/CT检查中,能够给予的有效剂量(E)。有效剂量将根据背景等效辐射时间(BERT)来表示,同时还将研究CT扫描对总剂量的贡献。

材料与方法

每个检查程序的有效剂量通过外部辐射剂量(CT部分)和内部辐射剂量(放射性药物给药)之和来计算。通过广泛的文献检索收集各方数据。

结果

展示了与每个检查程序相关的最小和最大有效剂量范围[E(min),E(max)]。这些剂量范围为0.5至49.1毫希沃特。BERT范围为2.6个月至20.4年。根据图像采集方案及其目的,CT对总有效剂量的贡献从2.1%到93%不等。与用于衰减校正和解剖定位的CT采集剂量相比,进行诊断性CT扫描会使剂量增加高达4.3倍。

结论

本文关注多模态检查程序中能够给予的有效剂量水平,同时要记住这些数据会不断变化,应定期更新。了解添加CT扫描时的剂量学影响很重要。根据研究指征应用优化方案可在不损失重要信息的情况下减少患者的辐射暴露。

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