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使用微型角膜刀制备的组织进行DSAEK术后的角膜屈光力

Corneal power after DSAEK using microkeratome-prepared tissues.

作者信息

de Sanctis Ugo, Angeloni Marco, Zilio Cristina, Sacco Diego, Grignolo Federico

机构信息

Department of Clinical Physiopathology, Ophthalmology Institute, University of Turin, Turin, Italy.

出版信息

Optom Vis Sci. 2011 Jun;88(6):697-702. doi: 10.1097/OPX.0b013e3182160763.

Abstract

PURPOSE

To investigate changes of corneal power after descemet stripping automated endothelial keratoplasty (DSAEK).

METHODS

Anterior, posterior, and true-net (anterior + posterior) power of post-DSAEK and contralateral transparent corneas were measured, using the Pentacam rotating Scheimpflug camera (Oculus Wetzlar, Germany), 6 months after surgery in 23 consecutive patients who had undergone unilateral DSAEK at the same medical center. Moreover, in each cornea, Pentacam pachimetry was measured at the vertex and at 3 mm from the vertex, to calculate corneal thickness increase (CTI).

RESULTS

In post-DSAEK corneas, the anterior power on average decreased by -0.24 ± 0.61 diopters (D), the negative posterior power increased by -0.96 ± 0.42 D, and the true-net power decreased by -1.19 ± 0.74 D (range: +0.17 to -2.23 D). Differences vs. contralateral transparent corneas did not reach statistical significance for anterior (p = 0.09) but were significant (p < 0.001) for posterior and true-net corneal power. CTI at 3 mm from the vertex was statistically larger (p < 0.0001) in post-DSAEK corneas (mean values 0.27 ± 0.07 vs. 0.12 ± 0.05); CTI values showed a statistically significant (p < 0.05) correlation with negative posterior corneal power values in post-DSAEK (r = -0.55) and in contralateral corneas (r = -0.67).

CONCLUSIONS

In comparison with contralateral corneas, post-DSAEK corneas show a moderate reduction of the true-net corneal power measured by Pentacam. Knowledge of true-net corneal power changes might be useful in adjusting K values and calculating intraocular lens power, in eyes scheduled for DSAEK combined with intraocular lens implantation/exchange.

摘要

目的

研究深板层角膜内皮移植术(DSAEK)后角膜屈光力的变化。

方法

使用Pentacam旋转式Scheimpflug相机(德国韦茨拉尔奥culus公司),对在同一医疗中心接受单侧DSAEK手术的23例连续患者术后6个月的DSAEK术后角膜及对侧透明角膜的前表面、后表面和真实净值(前表面+后表面)屈光力进行测量。此外,在每个角膜的顶点及距顶点3mm处测量Pentacam测厚值,以计算角膜厚度增加量(CTI)。

结果

在DSAEK术后角膜中,前表面屈光力平均降低-0.24±0.61屈光度(D),后表面负屈光力增加-0.96±0.42D,真实净值屈光力降低-1.19±0.74D(范围:+0.17至-2.23D)。与对侧透明角膜相比,前表面屈光力差异无统计学意义(p=0.09),而后表面和真实净值角膜屈光力差异有统计学意义(p<0.001)。DSAEK术后角膜距顶点3mm处的CTI在统计学上更大(p<0.0001)(平均值0.27±0.07对0.12±0.05);CTI值与DSAEK术后(r=-0.55)及对侧角膜(r=-0.67)的后表面负角膜屈光力值存在统计学显著相关性(p<0.05)。

结论

与对侧角膜相比,DSAEK术后角膜经Pentacam测量的真实净值角膜屈光力有适度降低。了解真实净值角膜屈光力变化可能有助于调整K值并计算计划行DSAEK联合人工晶状体植入/置换手术患者的人工晶状体屈光力。

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