Philippine National Ear Institute, National Institutes of Health, Manila, Philippines.
Otol Neurotol. 2011 Jun;32(4):539-43. doi: 10.1097/MAO.0b013e3182117782.
Tuberculosis (TB) is a rare cause of otitis media. This study aims to increase awareness on the clinical presentation of TB otitis media and illustrate how early detection affects treatment outcome.
Chart review of 12 patients (13 ears) from a tertiary hospital in Manila, Philippines, seen from 2004 to 2009. Clinical predictors of the disease were summarized. Clinical, radiologic, and audiometric outcomes after treatment were compared between treatment groups.
The 5 otoscopic presentations were multiple perforations, single perforation with refractory otorrhea and exuberant granulation tissue formation, single perforation with minimal otorrhea and no granulation tissue formation, intact tympanic membrane with middle ear effusion, and intact tympanic membrane with tumorlike tissue in the middle ear. Clinical predictors of the disease were history of pulmonary TB, work-related contamination of the infection, positive purified protein derivative test, positive chest radiographic finding and intraoperative granulation tissue with cheesy material, and temporal bone computed tomographic scan findings. Patients who had no middle ear surgery showed significantly better clinical, radiologic, and audiometric outcomes than those who were diagnosed late and had more complicated surgical procedure.
The clinical presentation of TB otitis media is variable. Early detection of the early forms entail less surgical intervention and favors better treatment results.
结核病(TB)是中耳炎的罕见病因。本研究旨在提高对 TB 中耳炎临床表现的认识,并说明早期发现如何影响治疗结果。
对 2004 年至 2009 年期间在菲律宾马尼拉一家三级医院就诊的 12 名患者(13 耳)进行图表回顾。总结了疾病的临床预测因素。比较了治疗组之间治疗后的临床、影像学和听力结果。
5 种耳镜表现为多个穿孔、单个穿孔伴难治性耳漏和过度肉芽组织形成、单个穿孔伴少量耳漏和无肉芽组织形成、鼓膜完整伴中耳积液、鼓膜完整伴中耳内肿瘤样组织。疾病的临床预测因素包括肺结核病史、与工作相关的感染污染、纯化蛋白衍生物试验阳性、胸部 X 线检查阳性和术中肉芽组织伴干酪样物质以及颞骨计算机断层扫描发现。未行中耳手术的患者的临床、影像学和听力结果明显优于诊断较晚且手术更复杂的患者。
TB 中耳炎的临床表现多种多样。早期发现早期形式需要较少的手术干预,并有利于更好的治疗结果。