X 连锁的 AP3A，是长距紫露草和剪秋罗中 Y 连锁的 MADS 框基因 AP3Y 的同源基因。
X linkage of AP3A, a homolog of the Y-linked MADS-box gene AP3Y in Silene latifolia and S. dioica.
机构信息
Department of Biology, Indiana University, Bloomington, Indiana, United States of America.
出版信息
PLoS One. 2011 Apr 20;6(4):e18972. doi: 10.1371/journal.pone.0018972.
BACKGROUND
The duplication of autosomal genes onto the Y chromosome may be an important element in the evolution of sexual dimorphism. A previous cytological study reported on a putative example of such a duplication event in a dioecious tribe of Silene (Caryophyllaceae): it was inferred that the Y-linked MADS-box gene AP3Y originated from a duplication of the reportedly autosomal ortholog AP3A. However, a recent study, also using cytological methods, indicated that AP3A is X-linked in Silene latifolia.
METHODOLOGY/PRINCIPAL FINDINGS: In this study, we hybridized S. latifolia and S. dioica to investigate whether the pattern of X linkage is consistent among distinct populations, occurs in both species, and is robust to genetic methods. We found inheritance patterns indicative of X linkage of AP3A in widely distributed populations of both species.
CONCLUSIONS/SIGNIFICANCE: X linkage of AP3A and Y linkage of AP3Y in both species indicates that the genes' ancestral progenitor resided on the autosomes that gave rise to the sex chromosomes and that neither gene has moved between chromosomes since species divergence. Consequently, our results do not support the contention that inter-chromosomal gene transfer occurred in the evolution of SlAP3Y from SlAP3A.
背景
常染色体基因复制到 Y 染色体上可能是性二态性进化的一个重要因素。先前的细胞学研究报告了石竹科半边莲属中存在这样的基因复制事件：据推测，Y 连锁的 MADS 框基因 AP3Y 来源于据称常染色体直系同源物 AP3A 的复制。然而，最近的一项也使用细胞学方法的研究表明，AP3A 在 Silene latifolia 中是 X 连锁的。
方法/主要发现：在这项研究中，我们对 S. latifolia 和 S. dioica 进行了杂交，以调查 X 连锁的模式是否在不同种群中一致，是否存在于两个物种中，以及是否对遗传方法具有稳健性。我们发现，在两个物种的广泛分布种群中，AP3A 具有 X 连锁的遗传模式。
结论/意义：AP3A 在两个物种中的 X 连锁和 AP3Y 在 Y 染色体上的连锁表明，这些基因的祖先位于产生性染色体的常染色体上，并且自物种分化以来，这两个基因都没有在染色体之间移动。因此，我们的结果不支持 SlAP3Y 从 SlAP3A 进化过程中发生染色体间基因转移的观点。
Zotero 插件