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药物过度使用性偏头痛的治疗有何未来?

What future for treatment of chronic migraine with medication overuse?

机构信息

Department of Neurological Sciences, Headache Unit, Neurological Institute C.Besta IRCCS Foundation, Via Celoria 11, 20133 Milan, Italy.

出版信息

Neurol Sci. 2011 May;32 Suppl 1:S19-22. doi: 10.1007/s10072-011-0553-0.

Abstract

Chronic headaches have increasingly become a focus within the field of head pain. Most of the patients with frequent headache eventually overuse their medications, and if it happens [the percentage is approximately 4%], the diagnosis of chronic migraine with medication-overuse headache is clinically important, because patients rarely respond to preventive medications while overusing acute medications. This kind of headache is recognized as a biobehavioral disorder, a complex condition wherein emotion and pain are intermingled. Properly treating medication overuse with adequate strategies by different and specific steps are essential components for helping these patients to improve and for preventing relapses. The clinical experience performed at our Headache Unit, the necessity of withdrawal, different treatment schedules, and different treatment strategies of our center were discussed.

摘要

慢性头痛已成为头痛领域的一个关注焦点。大多数经常头痛的患者最终会过度使用药物,如果发生这种情况[大约有 4%的患者],则需要对药物过度使用性头痛的慢性偏头痛做出临床诊断,因为患者在过度使用急性药物时很少对预防药物产生反应。这种头痛被认为是一种生物行为障碍,是一种情绪和疼痛交织在一起的复杂情况。通过不同的、特定的步骤,用适当的策略正确治疗药物滥用是帮助这些患者改善病情和预防复发的重要组成部分。我们头痛科的临床经验、戒断的必要性、不同的治疗方案以及我们中心的不同治疗策略都进行了讨论。

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