Khaengkhor Pranee, Mairaing Karicha, Suwannarurk Komsun, Thaweekul Yudthadej, Poomtavorn Yenruedee, Pattaraarchachai Junya, Bhamarapravatana Kornkarn
Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
J Med Assoc Thai. 2011 Feb;94(2):152-8.
To determine the prevalence of abnormal cervical cytology by liquid based cytology (LBC) in pregnant women who attended the antenatal care clinic at Thammasat University Hospital.
LBC was performed on specimens from the collecting vial containing preserved cell solution (Cytyc, Boxborough, MA) in pregnant women who attended antenatal care at the antenatal care clinic, Thammasat University Hospital between March and July 2010. One hundred forty three pregnant women were recruited in the present study. All cytological reports were reviewed by senior cytopathologists for accurate diagnosis using the Bethesda System 2001 criteria. Patients with abnormal results as "abnormal squamous/glandular cells of undetermined significant" or more over were referred for colposcopic examination.
One hundred forty three pregnant women participated in the present study. The average age was 27.09 years. There were 10 abnormal Pap smear results with four, five, and one cases of ASC-US, LSIL and HSIL respectively The prevalence of abnormal cervical cytology in this investigation was 7% with 0.7% high-grade cervical intraepithelial neoplacia. Only 6% of participants had the correct understanding of the necessity of Pap smear testing. Thirty-one percent of multiparous pregnant women in the present study had no previous Pap smear screening. The majority of participants had coitarche before the age of 20.
The prevalence of abnormal cervical cytology in pregnant patients attending the antenatal care clinic at Thammasat University Hospital was 7%. The cervical cytology and related education were highly recommended in antenatal care clinic to increase cervical cancer screening coverage among reproductive age women.
确定在泰国法政大学医院产前保健诊所就诊的孕妇中，采用液基细胞学（LBC）检测异常宫颈细胞学的患病率。
2010年3月至7月期间，对在泰国法政大学医院产前保健诊所接受产前检查的孕妇，使用含有保存细胞溶液（Cytyc，马萨诸塞州博克斯伯勒）的收集瓶中的标本进行LBC检测。本研究招募了143名孕妇。所有细胞学报告均由资深细胞病理学家根据2001年贝塞斯达系统标准进行复查以获得准确诊断。结果为“意义不明确的异常鳞状/腺细胞”或更严重异常结果的患者被转诊进行阴道镜检查。
143名孕妇参与了本研究。平均年龄为27.09岁。巴氏涂片检查结果异常的有10例，其中非典型鳞状细胞不能明确意义（ASC-US）4例、低度鳞状上皮内病变（LSIL）5例、高度鳞状上皮内病变（HSIL）1例。本次调查中异常宫颈细胞学的患病率为7%，高级别宫颈上皮内瘤变的患病率为0.7%。只有6%的参与者正确理解了巴氏涂片检查的必要性。本研究中31%的经产妇此前未进行过巴氏涂片筛查。大多数参与者在20岁之前开始有性行为。
在泰国法政大学医院产前保健诊所就诊的孕妇中，异常宫颈细胞学的患病率为7%。强烈建议在产前保健诊所进行宫颈细胞学检查及相关教育，以提高育龄妇女宫颈癌筛查的覆盖率。
