• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

精氨酸外渗导致皮肤坏死。

Arginine extravasation leading to skin necrosis.

作者信息

Abraham Mary B, van der Westhuyzen Jasper, Khanna Vikrant

机构信息

Department of Paediatrics, Hervey Bay Hospital, Queensland, Australia.

出版信息

J Paediatr Child Health. 2012 Mar;48(3):E96-7. doi: 10.1111/j.1440-1754.2011.02074.x. Epub 2011 Apr 29.

DOI:10.1111/j.1440-1754.2011.02074.x
PMID:21535285
Abstract

Arginine hydrochloride is used in the evaluation of short stature and in the management of urea cycle disorders. In recent times, it has been used in the treatment of stroke-like episodes of MELAS (mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes). We want to highlight the need for good intravenous access and monitoring the drip site to prevent extravasation injuries that can be caused by arginine, which is a hyperosmolar solution.

摘要

盐酸精氨酸用于评估身材矮小以及治疗尿素循环障碍。近年来,它还被用于治疗线粒体脑肌病伴高乳酸血症和卒中样发作(MELAS)的卒中样发作。我们想强调的是,由于盐酸精氨酸是高渗溶液,需要良好的静脉通路并监测滴注部位,以防止其可能导致的外渗损伤。

相似文献

1
Arginine extravasation leading to skin necrosis.精氨酸外渗导致皮肤坏死。
J Paediatr Child Health. 2012 Mar;48(3):E96-7. doi: 10.1111/j.1440-1754.2011.02074.x. Epub 2011 Apr 29.
2
Cutaneous necrosis induced by extravasation of arginine monohydrochloride.盐酸精氨酸外渗所致皮肤坏死
Acta Derm Venereol. 2008;88(3):310-1. doi: 10.2340/00015555-0420.
3
Case of skin necrosis due to arginine monohydrochloride extravasation.一例因盐酸精氨酸外渗导致皮肤坏死的病例。
J Dermatol. 2007 Mar;34(3):198-200. doi: 10.1111/j.1346-8138.2007.00249.x.
4
Necrosis caused by extravasation of arginine hydrochloride.盐酸精氨酸外渗引起的坏死。
Ann Pharmacother. 1992 Feb;26(2):263-4. doi: 10.1177/106002809202600226.
5
Mitochondrial encephalopathy, lactic acidosis, and strokelike episodes: basic concepts, clinical phenotype, and therapeutic management of MELAS syndrome.线粒体脑肌病、乳酸酸中毒和卒中样发作:MELAS综合征的基本概念、临床表型及治疗管理
Ann N Y Acad Sci. 2008 Oct;1142:133-58. doi: 10.1196/annals.1444.011.
6
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes.线粒体脑肌病、乳酸酸中毒及卒中样发作
Neurosciences (Riyadh). 2011 Apr;16(2):162-3.
7
Full-thickness skin necrosis after arginine extravasation--a case report and review of literature.精氨酸外渗后全层皮肤坏死——1例病例报告及文献复习
J Pediatr Surg. 2004 Apr;39(4):e9-11. doi: 10.1016/j.jpedsurg.2003.12.030.
8
Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study.左乙拉西坦给药与线粒体脑肌病、乳酸酸中毒和卒中样发作患者的死亡率降低相关:一项回顾性研究。
Chin Med J (Engl). 2019 Feb 5;132(3):269-274. doi: 10.1097/CM9.0000000000000061.
9
Management of arginine monohydrochloride extravasation in the forearm.前臂精氨酸盐酸盐外渗的处理
South Med J. 1991 Mar;84(3):381-4. doi: 10.1097/00007611-199103000-00018.
10
Beneficial effect of L-arginine for stroke-like episode in MELAS.L-精氨酸对线粒体脑肌病伴乳酸血症和卒中样发作(MELAS)患者卒中样发作的有益作用。
Brain Dev. 2004 Oct;26(7):481-3; discussion 480. doi: 10.1016/j.braindev.2004.01.006.

引用本文的文献

1
Cutaneous Management after Extravasation of High-Concentrated Amino Acid Solution Administered for Renal Protection in PRRT.PRRT 中应用高浓度氨基酸溶液进行肾脏保护时发生外渗的皮肤处理
Tomography. 2022 Feb 3;8(1):356-363. doi: 10.3390/tomography8010029.
2
Extravasation Injuries of the Limbs in Neonates and Children—Development of a Treatment Algorithm.新生儿和儿童四肢外渗损伤——治疗方案的制定。
Dtsch Arztebl Int. 2021 Aug 23;118(33-34):547-554. doi: 10.3238/arztebl.m2021.0220.
3
An Introduction to Pharmacotherapy for Inborn Errors of Metabolism.
先天性代谢缺陷的药物治疗导论
J Pediatr Pharmacol Ther. 2018 Nov-Dec;23(6):432-446. doi: 10.5863/1551-6776-23.6.432.
4
Nitric oxide synthesis is increased in cybrid cells with m.3243A>G mutation.在具有m.3243A>G突变的杂交细胞中,一氧化氮的合成增加。
Int J Mol Sci. 2012 Dec 24;14(1):394-410. doi: 10.3390/ijms14010394.