Abraham Mary B, van der Westhuyzen Jasper, Khanna Vikrant
Department of Paediatrics, Hervey Bay Hospital, Queensland, Australia.
J Paediatr Child Health. 2012 Mar;48(3):E96-7. doi: 10.1111/j.1440-1754.2011.02074.x. Epub 2011 Apr 29.
Arginine hydrochloride is used in the evaluation of short stature and in the management of urea cycle disorders. In recent times, it has been used in the treatment of stroke-like episodes of MELAS (mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes). We want to highlight the need for good intravenous access and monitoring the drip site to prevent extravasation injuries that can be caused by arginine, which is a hyperosmolar solution.
盐酸精氨酸用于评估身材矮小以及治疗尿素循环障碍。近年来,它还被用于治疗线粒体脑肌病伴高乳酸血症和卒中样发作(MELAS)的卒中样发作。我们想强调的是,由于盐酸精氨酸是高渗溶液,需要良好的静脉通路并监测滴注部位,以防止其可能导致的外渗损伤。