Nunn-Brooks Lindsey, Michael Robin, Ravitz Lea B, Kordick Dorsey, Lappin Michael R
Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
J Feline Med Surg. 2011 Aug;13(8):622-4. doi: 10.1016/j.jfms.2011.03.003. Epub 2011 May 4.
Otodectes cynotis infestation is common in kittens housed in crowded environments like animal shelters. It is unknown how rapidly O cynotis is killed within the first 72h of treatment with currently available products. Kittens ≥4 weeks of age with live O cynotis in both ears (AU) were administered 0.5ml of 0.01% ivermectin otic suspension (Acarexx; Idexx Pharmaceuticals) once, AU or selamectin (Revolution; Pfizer Animal Health) once, on the skin following the manufacturer's instructions. Repeat microscopic examination was performed on individual ears based on a randomization schedule during the 72h after treatment. There was no evidence of toxicity with either drug and administration of 0.01% ivermectin significantly reduced the time to live mite-free status compared to selamectin. Both drugs have an effect against O cynotis as early as 10-12h after administration with an increasing effect over time.
耳痒螨感染在动物收容所等拥挤环境中饲养的小猫中很常见。目前尚不清楚使用现有产品治疗后的头72小时内耳痒螨被杀死的速度有多快。对双耳均有活耳痒螨的≥4周龄小猫，按照制造商说明，每侧耳朵一次给予0.5ml 0.01%伊维菌素耳用混悬液（Acarexx；爱德士制药公司），或者在皮肤上一次给予塞拉菌素（瑞辉；辉瑞动物保健公司）。治疗后72小时内，根据随机安排对每只耳朵进行重复显微镜检查。两种药物均未出现毒性迹象，与塞拉菌素相比，给予0.01%伊维菌素显著缩短了达到无活螨状态的时间。两种药物在给药后10 - 12小时就对耳痒螨有作用，且随着时间推移作用增强。
