Costa Daniela Otero Pereira da, Alves Adriana Terezinha Neves Novellino, Calasans-Maia Mônica Diuna, Cruz Ricardo Lopes da, Lourenço Simone de Queiroz Chaves
Department of Pathology, Fluminense Federal University, Niterói, RJ, Brazil.
Braz Dent J. 2011;22(2):171-4. doi: 10.1590/s0103-64402011000200015.
Ameloblastic fibroma is a relatively rare benign odontogenic tumor in which both the epithelial and ectomesenchymal components are neoplastic. An 8-year-old Caucasian boy was referred to the dentist for evaluation of failed eruption of the maxillary left first molar. The panoramic radiograph showed a well-circumscribed unilocular radiolucency involving an unerupted maxillary left first permanent molar. The lesion was enucleated and the material was sent for histopathologic examination. Microscopically, it was composed by cords and islands of odontogenic epithelium in a myxoid cell-rich stroma that closely resemble the dental papilla with histopathological diagnosis of ameloblastic fibroma. After 24 months of follow-up no recurrence was observed and the maxillary left first molar erupted spontaneously through the buccal mucosa and was aligned with a fixed orthodontic appliance. This case emphasized the importance of careful differential diagnosis of intraosseous oral lesions and reported a rarity of the lesion and its atypical location.
成釉细胞纤维瘤是一种相对罕见的良性牙源性肿瘤,其上皮和外间充质成分均为肿瘤性。一名8岁的白种男孩因上颌左侧第一磨牙萌出失败被转诊至牙医处进行评估。全景X线片显示一个边界清晰的单房性透射区,累及未萌出的上颌左侧第一恒磨牙。病变被摘除,标本送去做组织病理学检查。显微镜下,它由牙源性上皮条索和岛状结构组成,位于富含黏液样细胞的基质中,与牙乳头非常相似,组织病理学诊断为成釉细胞纤维瘤。经过24个月的随访,未观察到复发,上颌左侧第一磨牙自行穿破颊黏膜萌出,并通过固定正畸矫治器排齐。该病例强调了对骨内口腔病变进行仔细鉴别诊断的重要性,并报告了该病变的罕见性及其非典型位置。