Department of Forensic Molecular Biology, Erasmus MC – University Medical Center Rotterdam, The Netherlands.
Br J Sports Med. 2012 Jun;46(8):614-7. doi: 10.1136/bjsm.2010.082552. Epub 2011 May 3.
Based on DNA analysis of a historical case, the authors describe how a female athlete can be unknowingly confronted with the consequences of a disorder of sex development resulting in hyperandrogenism emerging early in her sports career. In such a situation, it is harmful and confusing to question sex and gender. Exposure to either a low or high level of endogenous testosterone from puberty is a decisive factor with respect to sexual dimorphism of physical performance. Yet, measurement of testosterone is not the means by which questions of an athlete's eligibility to compete with either women or men are resolved. The authors discuss that it might be justifiable to use the circulating testosterone level as an endocrinological parameter, to try to arrive at an objective criterion in evaluating what separates women and men in sports competitions, which could prevent the initiation of complicated, lengthy and damaging sex and gender verification procedures.
基于对一个历史案例的 DNA 分析，作者描述了一名女性运动员如何在其运动生涯早期不知不觉地面临因雄激素过多症而导致的性别发育障碍的后果。在这种情况下，质疑性别会带来伤害和困惑。青春期暴露于低水平或高水平的内源性睾酮是决定身体表现性别差异的决定性因素。然而，测量睾酮并不是解决运动员是否有资格与女性或男性竞争的问题的方法。作者认为，使用循环睾酮水平作为内分泌参数来尝试确定体育竞赛中区分女性和男性的客观标准可能是合理的，这可以防止启动复杂、冗长和具有破坏性的性别验证程序。
