Gómez Sandra L, Palma Alirio, Cobo Justo, Glidewell Christopher
Laboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678 Bucaramanga, Colombia.
Acta Crystallogr C. 2011 May;67(Pt 5):o157-60. doi: 10.1107/S010827011101016X. Epub 2011 Apr 12.
The title compound, C(15)H(16)N(2)O, crystallizes in the space group P2(1)2(1)2(1) with Z' = 1. The seven-membered ring adopts a chair-type conformation with the hydroxy and pyridyl substituents in equatorial sites. Molecules are linked into a three-dimensional framework structure by a combination of O-H···N, C-H···O and C-H···π(arene) hydrogen bonds, but N-H···O and N-H···π(arene) interactions are absent from the structure. Comparisons are made with some related compounds.
标题化合物C(15)H(16)N(2)O以Z' = 1结晶于空间群P2(1)2(1)2(1)中。七元环呈椅式构象，羟基和吡啶基取代基位于赤道位置。分子通过O-H···N、C-H···O和C-H···π(芳烃)氢键的组合连接成三维骨架结构，但该结构中不存在N-H···O和N-H···π(芳烃)相互作用。与一些相关化合物进行了比较。
