Department of Radiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 310016 Hangzhou, China.
Int J Cardiovasc Imaging. 2012 Feb;28(2):415-23. doi: 10.1007/s10554-011-9822-5. Epub 2011 May 4.
To investigate the image quality and dose performance of 80 kV high-pitch spiral (HPS) coronary CT angiography (CCTA). 106 patients consecutively enrolled into prospectively ECG-triggering HPS CCTA (pitch = 3.4) exam using kV/ref. mAs = 80/400, 100/370, and 120/370 when patient BMI was ≤22.5 (n = 40), between 22.5 and 27.5 (n = 53) and >27.5 kg/m² (n = 13). Image quality was assessed per-segment by two observers independently using a 4-point scale (1-excellent, 4-non-diagnosable). Image noise and signal-to-noise ratio (SNR), contrast-to-noise ratio were measured. Diagnostic image quality was obtained in 503 of 507, 687 of 693, 164 of 167 coronary segments in 80, 100, 120 kV groups without significant difference (P = 0.482). The proportions of segments with score 1-4 were not significantly different among three kV groups (all P > 0.05). Image noise were significantly higher in 80 kV group than 100 and 120 groups (P < 0.001), while SNR was not (P = 0.097). The effective dose of 80 kV group (0.36 ± 0.03 mSv) was significantly lower than that of 100 kV group (0.86 ± 0.08 mSv) and 120 kV group (1.77 ± 0.18 mSv). The mean ± SD of HR in all patients was 54.8 ± 5.1 bpm. 80 kV HPS CCTA is feasible for patient with BMI ≤ 22.5 kg/m² which can save 58% dose than 100 kV group, while maintain diagnosable image quality.
为了研究 80kV 高螺距螺旋（HPS）冠状动脉 CT 血管造影（CCTA）的图像质量和剂量性能。连续纳入 106 例前瞻性心电图触发 HPS CCTA（螺距=3.4）检查的患者，当 BMI 为≤22.5kg/m²（n=40）、22.5kg/m²至 27.5kg/m²（n=53）和>27.5kg/m²（n=13）时，管电压/参考 mAs 分别为 80/400、100/370 和 120/370。两位观察者独立使用 4 分制评估每段图像质量（1-极好，4-不可诊断）。测量图像噪声和信噪比（SNR）、对比噪声比。在 80、100、120kV 组中，507、693、167 个冠状动脉段中有 503、687、164 个段获得了诊断性图像质量，差异无统计学意义（P=0.482）。三组间各管电压组具有 1-4 分的段数比例无显著差异（均 P>0.05）。80kV 组图像噪声明显高于 100kV 和 120kV 组（P<0.001），而 SNR 无差异（P=0.097）。80kV 组有效剂量（0.36±0.03mSv）明显低于 100kV 组（0.86±0.08mSv）和 120kV 组（1.77±0.18mSv）。所有患者的平均 HR±SD 为 54.8±5.1bpm。对于 BMI≤22.5kg/m²的患者，80kV HPS CCTA 是可行的，可比 100kV 组节省 58%的剂量，同时保持可诊断的图像质量。
