Miklos P, Babala P, Klacko M, Masák L, Ondrus D
Klinika gynekologickej onkológie OUSA a SZU Bratislava, Slovenská republika 21. onkologicka klinika LF UK a OUSA Bratislava, Slovenská republika.
Klin Onkol. 2011;24(1):50-3.
HPV infections of the lower genital tract are associated with the increasing incidence of vulvar intraepithelial neoplasia. The new classification divides vulvar intraepithelial neoplasia according to its incidence into two groups: usual and differentiated type. The usual type occurs mainly in young women and is associated with HPV infection, the differentiated type is HPV-negative and occurs in older women. The diagnosis is based on biopsy from a suspicious lesion. The standard treatment involves surgical excision. Topical treatment is now being preferred in young women in order to preserve appearance of the genitalia and sexual function. The high risk of recurrence is the reason for strict monitoring of patients after treatment completion.
下生殖道的人乳头瘤病毒（HPV）感染与外阴上皮内瘤变发病率的上升有关。新的分类根据外阴上皮内瘤变的发病率将其分为两组：普通型和分化型。普通型主要发生在年轻女性中，与HPV感染有关，分化型HPV阴性，发生在老年女性中。诊断基于对可疑病变的活检。标准治疗包括手术切除。为了保留生殖器外观和性功能，目前年轻女性更倾向于局部治疗。复发风险高是治疗完成后对患者进行严格监测的原因。
