Pei Yue-hu, Hua Hui-ming, Li Zhan-lin, Chen Gang
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
Yao Xue Xue Bao. 2011 Feb;46(2):127-31.
In the structural determination of natural glycosides, nuclear magnetic resonance (NMR) is an important approach in determining the configuration of glycoside bond. The test of coupling constant of the anomeric proton and chemical shift of the anomeric carbon are two common methods, but these methods are not suitable for some sugars. For those sugars, detailed 13C NMR analysis is an alternative choice. This paper summarizes the characteristics of 1H and 13C NMR data of the common monosaccharides published in the literatures, in order to search an approach to determine the configuration of glycoside bond.
在天然糖苷的结构测定中，核磁共振（NMR）是确定糖苷键构型的重要方法。端基质子偶合常数的测定和端基碳化学位移的测定是两种常用方法，但这些方法不适用于某些糖类。对于那些糖类，详细的13C NMR分析是一种替代选择。本文总结了文献中报道的常见单糖的1H和13C NMR数据特征，以便寻找一种确定糖苷键构型的方法。
