Antipova V N, Lomaeva M G
Genetika. 2011 Mar;47(3):425-7.
A novel large mtDNA deletion of 5914 bp was detected in mice exposed to X-radiation. The regions flanking the deleted fragment were characterized by the method of sequencing. The possibility of using a minimum sample of the mouse auricle tissue for detecting mtDNA deletions in the same animals at different postradiation times is demonstrated.
在接受X射线辐射的小鼠中检测到一个新的5914 bp的大片段线粒体DNA(mtDNA)缺失。通过测序方法对缺失片段两侧的区域进行了表征。证明了使用小鼠耳廓组织的最小样本在不同辐射后时间检测同一动物体内mtDNA缺失的可能性。