Mezentseva L V
Biofizika. 2011 Mar-Apr;56(2):322-7.
A computer model of excitation conduction in the heart has been employed to study the nonlinear heart rate dynamics under stress loads. The modeling was aimed to test the hypothesis explaining changes in the heart rate dynamics during nociceptive stress loads by the occurrence of train extracardial impulsation arriving at the sinoatrial node. The computer simulation shows that, with a particular set of parameters, the model imitates the dynamics of RR intervals observed in experiments. The present model provides a unified theoretical basis for further simulation of various types of ventricular disturbances under external extreme loads.
心脏兴奋传导的计算机模型已被用于研究应激负荷下的非线性心率动力学。该建模旨在检验一种假说，即通过到达窦房结的一系列心外冲动的出现来解释伤害性应激负荷期间心率动力学的变化。计算机模拟表明，在特定的一组参数下，该模型模仿了实验中观察到的RR间期的动力学。本模型为进一步模拟外部极端负荷下各种类型的心室紊乱提供了统一的理论基础。
