Arthritis Res Ther. 2011 Apr 19;13(2):107. doi: 10.1186/ar3290.
Hyperuricemia is the most important risk factor for gouty arthritis. The quandary is how to predict which patient with asymptomatic hyperuricemia will develop gouty arthritis. Can ultrasonography help identify hyperuricemic individuals at risk for developing gouty arthritis? In the previous issue of Arthritis Research & Therapy, Pineda and colleagues found ultrasonography changes suggestive of gouty arthritis in 25% of hyperuricemic individuals. These were found exclusively in hyperuricemic individuals but not in normouricemic patients. Ultrasonography may serve as a noninvasive means to diagnose gouty arthritis in hyperuricemic individuals who have yet to develop symptomatic gouty arthritis.
高尿酸血症是痛风性关节炎最重要的危险因素。难题在于如何预测哪些无症状高尿酸血症患者会发展为痛风性关节炎。超声检查能否帮助识别有发生痛风性关节炎风险的高尿酸血症个体?在《关节炎研究与治疗》杂志的前一期中,Pineda 及其同事发现,25%的高尿酸血症个体存在超声检查提示痛风性关节炎的改变。这些改变仅见于高尿酸血症个体,而不见于血尿酸正常者。超声检查可能成为一种无创手段,用于诊断尚未出现有症状痛风性关节炎的高尿酸血症个体的痛风性关节炎。