Department of Medical Oncology, Lyon University, Hospices Civils de Lyon, Pierre-Bénite Cédex, France.
Int J Gynecol Cancer. 2011 May;21(4):776-81. doi: 10.1097/IGC.0b013e31821bb700.
Elderly patients are more commonly diagnosed with advanced ovarian cancer and represent a growing proportion of all ovarian cancer cases. Despite this, the elderly have historically been underrepresented in clinical trials. Because clinical trials form the basis for most treatment guidelines and the elderly have been, to date, largely excluded from this process, little is known about the appropriate assessment and treatment of elderly ovarian cancer patients. Recognizing this knowledge deficit and the pressing need to correct it, this article aimed to summarize existing data and identify future areas of research focus.
老年患者更常被诊断为晚期卵巢癌，且在所有卵巢癌病例中所占比例不断增加。尽管如此，老年患者在临床试验中历来代表性不足。由于临床试验是大多数治疗指南的基础，而迄今为止，老年人在很大程度上被排除在这一过程之外，因此对于老年卵巢癌患者的适当评估和治疗知之甚少。鉴于这一知识缺陷以及纠正这一缺陷的迫切需要，本文旨在总结现有数据并确定未来的研究重点。
