Department of Public Health, Ghent University, Belgium.
J Hum Hypertens. 2012 Jun;26(6):381-7. doi: 10.1038/jhh.2011.42. Epub 2011 May 5.
The underlying pathogenetic mechanisms of nondipping blood pressure (BP) pattern are not completely understood. Especially the role of psychosocial correlates remains unclear. The aim was to assess the association between nondipping BP pattern, behavioural and psychosocial factors in a sample of working men and women. The study sample included 167 working men and women aged 40-64 years from the BELSTRESS cohort. Socio-demographic, behavioural and psychosocial factors were assessed by self-administered questionnaires. Participants were medically examined and underwent an ambulatory BP monitoring during 24 h. Nondipping was defined when the average nocturnal decline in BP was <10%. The prevalence of nondipping for both systolic and diastolic BP was 7.8%. Nondipping was not significantly related to smoking, alcohol consumption and leisure time physical activity. A crude significant association was observed between nondipping and sleep problems. After adjusting for gender, education and body mass index, the risk for nondipping was associated with job strain, living alone, being unsatisfied about the contact with one's children, depressive symptoms and vital exhaustion. Nondipping BP pattern was consistently related to psychosocial factors in this study: positive associations were observed with measures of job strain, poor private life support (living alone and being unsatisfied about the contact with one's children) and mental health problems (depressive symptoms and vital exhaustion).
非杓型血压模式的潜在发病机制尚不完全清楚。特别是心理社会相关因素的作用仍不清楚。目的是评估在工作男性和女性样本中，非杓型血压模式、行为和心理社会因素之间的关系。该研究样本包括 BELSTRESS 队列中 167 名年龄在 40-64 岁的在职男性和女性。通过自我管理问卷评估社会人口统计学、行为和心理社会因素。参与者接受了医学检查，并进行了 24 小时动态血压监测。当平均夜间血压下降<10%时，定义为非杓型。收缩压和舒张压的非杓型患病率均为 7.8%。非杓型与吸烟、饮酒和休闲时间体力活动无显著相关性。在调整了性别、教育和体重指数后，非杓型与工作压力、独居、对与子女的接触不满意、抑郁症状和活力耗竭有关。在这项研究中，非杓型血压模式与心理社会因素始终相关：与工作压力、私人生活支持差（独居和对与子女的接触不满意）和心理健康问题（抑郁症状和活力耗竭）呈正相关。
