Michalaki Vasiliki, Zygogianni Anna, Kouloulias Vassilios, Balafouta Myrsini, Vlachodimitropoulos Dimitrios, Gennatas Constantine G
Radiology Department, Aretaieion University Hospital, University of Athens, Athens, Greece.
J Cancer Res Ther. 2011 Jan-Mar;7(1):81-3. doi: 10.4103/0973-1482.80467.
Hepatocellular carcinoma is the most common primary tumor of the liver. Disease dissemination occurs through hematogenous routes and frequently involves the lungs, bone, adrenal glands, and pancreas. The patterns of the extrahepatic manifestations are diverse. Soft tissue metastasis is extremely rare and mandates systematic pathological analysis, which may include the use of specific immunohistochemical staining. We report metastasis from a hepatocellular carcinoma, as a discrete subcutaneous mass to the right humerus muscle.
We detail the approach to diagnosis and management of an unusual case of a patient with hepatocellular carcinoma, in whom we found a metastatic lesion as a subcutaneous mass to the right humerus muscle nine years after right hepatectomy.
This condition poses differential diagnostic problems in the settings of clinical and pathological investigations. Metastasis of hepatocellular carcinoma should be included in the differential diagnosis of rapidly growing lesions.
肝细胞癌是最常见的肝脏原发性肿瘤。疾病通过血行途径播散，常累及肺、骨、肾上腺和胰腺。肝外表现形式多样。软组织转移极为罕见，需要进行系统的病理分析，这可能包括使用特定的免疫组织化学染色。我们报告了一例肝细胞癌转移至右肱骨肌肉，表现为一个离散的皮下肿块。
我们详细阐述了一名肝细胞癌患者的诊断和处理方法，该患者在右肝切除术后九年，我们发现其右肱骨肌肉有一个作为皮下肿块的转移病灶。
这种情况在临床和病理检查中会带来鉴别诊断问题。肝细胞癌转移应纳入快速生长病变的鉴别诊断中。
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