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汞(II)离子介导的双链样 DNA 切割的切口内切酶的触发活性。

Triggered activity of a nicking endonuclease for mercuric(II) ion-mediated duplex-like DNA cleavage.

机构信息

College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, China.

出版信息

Chem Commun (Camb). 2011 Jun 14;47(22):6347-9. doi: 10.1039/c1cc11858g. Epub 2011 May 6.

Abstract

The cleavage activity of a nicking endonuclease towards metal-ion-mediated duplex-like DNA can be triggered by the corresponding metal ions, which was demonstrated with mercuric(II) ion as a model via a simple electrochemical protocol.

摘要

一种切割核酸内切酶对金属离子介导的双链样 DNA 的切割活性可以被相应的金属离子触发,这是通过一个简单的电化学方案,以汞(II)离子作为模型证明的。

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