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立体定向活检中 5-氨基酮戊酸用于确认脑深部肿瘤。附 2 例报告。

Use of 5-aminolevulinic acid for the confirmation of deep-seated brain tumors during stereotactic biopsy. Report of 2 cases.

机构信息

Department of Neurosurgery, Rinku General Medical Center, Izumisano, Osaka, Japan.

出版信息

J Neurosurg. 2011 Aug;115(2):278-80. doi: 10.3171/2011.4.JNS102137. Epub 2011 May 6.

DOI:10.3171/2011.4.JNS102137
PMID:21548751
Abstract

5-Aminolevulinic acid (ALA) has been successfully used to confirm the target tumor tissues obtained during stereotactic biopsy. The authors report their experience with 2 patients who underwent stereotactic biopsies of thalamic malignant lymphoma and pontine glioma utilizing 5-ALA. Intraoperatively, the tumor specimens fluoresced, allowing for confirmation that the obtained target specimen contained tumor tissues. No serious side effects or complications occurred.

摘要

5-氨基酮戊酸（ALA）已成功用于确认立体定向活检获得的靶肿瘤组织。作者报告了 2 例利用 5-ALA 行丘脑恶性淋巴瘤和桥脑胶质瘤立体定向活检的经验。术中，肿瘤标本发出荧光，证实获得的靶标本含有肿瘤组织。未发生严重的副作用或并发症。

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Use of 5-aminolevulinic acid for the confirmation of deep-seated brain tumors during stereotactic biopsy. Report of 2 cases.立体定向活检中 5-氨基酮戊酸用于确认脑深部肿瘤。附 2 例报告。
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