Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Gastrointest Endosc. 2011 Jul;74(1):44-50. doi: 10.1016/j.gie.2011.02.020. Epub 2011 May 6.
Self-expandable metals stents (SEMSs) have increasingly been used as a temporary device to bridge chemoradiotherapy in patients with malignant esophageal disease or in patients with benign esophageal defects or stenosis.
To evaluate the outcome of removal of SEMSs in a large cohort of patients with benign and malignant esophageal disease.
Observational study with standardized treatment and follow-up.
Single university center.
Between 2001 and 2010, 95 consecutive patients referred for endoscopic SEMS extraction were included.
Endoscopic stent removal.
Technical and functional outcome and complications.
A total of 124 stent extractions were undertaken in 95 patients; both partially covered (68%) and fully covered (32%) SEMSs were removed. Three patients had 2 overlapping SEMSs in place. Successful primary removal was achieved in 89%; the secondary removal rate was 96%. Uncomplicated primary removal rate was significantly higher for fully covered versus partially covered stents (P = .035) and for single versus overlapping stents (P = .033). Patients with a complicated stent removal had the stent in place significantly longer compared with patients with an uncomplicated primary stent removal (126 days vs 28 days; P = .01). Surgical removal was required in 3 patients (2.4%). Six moderate and severe complications (5%) related to the endoscopic extraction occurred.
Retrospective, nonrandomized study design.
Primary endoscopic removal of an SEMS is feasible in the majority of patients with benign and malignant esophageal disease. A longer time that a stent is in place and the use of partially covered SEMSs both impede removal. Moreover, overlapping SEMSs should be avoided for temporary use because stent disintegration and subsequent complications may occur.
自膨式金属支架(SEMS)已越来越多地被用作恶性食管疾病患者接受放化疗或良性食管缺损或狭窄患者的临时搭桥治疗手段。
评估大样本量良、恶性食管疾病患者中 SEMS 取出的结果。
标准化治疗和随访的观察性研究。
单所大学中心。
2001 年至 2010 年间,共有 95 例因内镜 SEMS 取出而就诊的连续患者被纳入。
内镜下支架取出。
技术和功能结果及并发症。
95 例患者共进行了 124 次支架取出;其中部分覆盖(68%)和完全覆盖(32%)SEMS 均被取出。3 例患者的支架重叠放置。初次取出成功率为 89%;二次取出成功率为 96%。完全覆盖支架与部分覆盖支架(P=.035)和单支架与重叠支架(P=.033)相比,初次取出成功率更高,且并发症发生率更低。复杂支架取出患者的支架放置时间明显长于初次简单支架取出患者(126 天 vs 28 天;P=.01)。3 例(2.4%)患者需要手术切除。6 例(5%)发生中度至严重并发症与内镜取出相关。
回顾性、非随机研究设计。
大多数良、恶性食管疾病患者可行 SEMS 初次内镜取出。支架放置时间较长和使用部分覆盖 SEMS 均会阻碍取出。此外,重叠 SEMS 应避免临时使用,因为可能会发生支架解体和随后的并发症。