Stein Matthew I, Park Justin, Raterman Stephen
Department of Orthopedic Surgery and Sports Medicine, University of South Florida, Tampa, Florida, USA.
Orthopedics. 2011 May;34(5):389-392. doi: 10.3928/01477447-20110317-21.
The often debilitating condition of hemophilic arthropathy is treated with elective total joint arthroplasty. Little has been published addressing the role of thromboembolic prophylaxis in the hemophilic patient population following total hip arthroplasty (THA) and total knee arthroplasty (TKA). Although the American College of Chest Physicians and the American Academy of Orthopaedic Surgeons have set guidelines for thromboembolic prophylaxis in the general population, no such standard of care is in place for hemophilic patients. While the risk of thrombosis in hemophilic patients following THA and TKA is thought to be lower, cases have been reported of pulmonary embolism and deep vein thrombosis (DVT) in hemophilic patients.
血友病性关节病这种常使人虚弱的病症采用择期全关节置换术进行治疗。关于全髋关节置换术（THA）和全膝关节置换术（TKA）后血栓栓塞预防在血友病患者群体中的作用，发表的相关内容很少。尽管美国胸科医师学会和美国矫形外科医师学会已经为普通人群制定了血栓栓塞预防指南，但血友病患者尚无这样的标准治疗方案。虽然认为血友病患者在THA和TKA后发生血栓形成的风险较低，但已有血友病患者发生肺栓塞和深静脉血栓形成（DVT）的病例报道。
