Roviello F, Caruso S, Marrelli D, Pedrazzani C, Neri A, De Stefano A, Pinto E
Universita degli Studi Siena, Policlinico Le Scotte, Dipartimento di Patologia Umana e Oncologia.
G Chir. 2011 Apr;32(4):211-33.
Pinto Peritoneal carcinomatosis (PC) had for long been regarded as a terminal disease, characterized by a very poor survival and worthy of being treated with palliative therapy only. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) provide a promising additional treatment option for patients with peritoneal carcinomatosis, resulting in recently published series enable to obtain long-term survival. In spite of the need for more high quality studies, there is now a consensus among many international experts about the use of this new strategy as gold standard for treating with intent of cure selected patients with PC. We summarized the present status and possible future progress of this treatment modality, in particular outlining its rationale, current practice and general outcomes.
平托 长期以来,腹膜癌病(PC)一直被视为一种终末期疾病,其特点是生存率极低,仅值得采用姑息治疗。细胞减灭术(CRS)和腹腔内热灌注化疗(HIPEC)为腹膜癌病患者提供了一种有前景的额外治疗选择,最近发表的系列研究表明能够实现长期生存。尽管仍需要更多高质量研究,但现在许多国际专家已就将这种新策略作为治愈特定PC患者的金标准治疗方法达成共识。我们总结了这种治疗方式的现状和未来可能的进展,尤其概述了其基本原理、当前实践和总体结果。