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人肺敏感层中β辐射剂量以及222Rn/220Rn子体所致的剂量转换系数。

Doses from beta radiation in sensitive layers of human lung and dose conversion factors due to 222Rn/220Rn progeny.

作者信息

Markovic V M, Stevanovic N, Nikezic D

机构信息

Department of Physics, Faculty of Science, University of Kragujevac, R. Domanovic 12, 34000, Kragujevac, Serbia.

出版信息

Radiat Environ Biophys. 2011 Aug;50(3):431-40. doi: 10.1007/s00411-011-0369-6. Epub 2011 May 10.

DOI:10.1007/s00411-011-0369-6
PMID:21556846
Abstract

Great deal of work has been devoted to determine doses from alpha particles emitted by (222)Rn and (220)Rn progeny. In contrast, contribution of beta particles to total dose has been neglected by most of the authors. The present work describes a study of the detriment of (222)Rn and (220)Rn progeny to the human lung due to beta particles. The dose conversion factor (DCF) was introduced to relate effective dose and exposure to radon progeny; it is defined as effective dose per unit exposure to inhaled radon or thoron progeny. Doses and DCFs were determined for beta radiation in sensitive layers of bronchi (BB) and bronchioles (bb), taking into account inhaled (222)Rn and (220)Rn progeny deposited in mucus and cilia layer. The nuclei columnar secretory and short basal cells were considered to be sensitive target layers. For dose calculation, electron-absorbed fractions (AFs) in the sensitive layers of the BB and bb regions were used. Activities in the fast and slow mucus of the BB and bb regions were obtained using the LUNGDOSE software developed earlier. Calculated DCFs due to beta radiation were 0.21 mSv/WLM for (222)Rn and 0.06 mSv/WLM for (220)Rn progeny. In addition, the influence of Jacobi room parameters on DCFs was investigated, and it was shown that DCFs vary with these parameters by up to 50%.

摘要

大量工作致力于确定由(222)Rn和(220)Rn子体发射的α粒子的剂量。相比之下,大多数作者都忽略了β粒子对总剂量的贡献。本研究描述了一项关于(222)Rn和(220)Rn子体因β粒子对人类肺部造成损害的研究。引入了剂量转换因子(DCF)来关联有效剂量和氡子体暴露;它被定义为每单位吸入氡或钍射气子体暴露的有效剂量。考虑到沉积在黏液和纤毛层中的吸入(222)Rn和(220)Rn子体,确定了支气管(BB)和细支气管(bb)敏感层中β辐射的剂量和DCF。核柱状分泌细胞和短基底细胞被视为敏感目标层。为了进行剂量计算,使用了BB和bb区域敏感层中的电子吸收分数(AFs)。BB和bb区域快速和慢速黏液中的活度是使用早期开发的LUNGDOSE软件获得的。(222)Rn子体因β辐射计算出的DCF为0.21 mSv/WLM,(220)Rn子体为0.06 mSv/WLM。此外,研究了雅可比室参数对DCF的影响,结果表明DCF随这些参数变化高达50%。

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Radiat Prot Dosimetry. 2010 Oct;141(4):428-31. doi: 10.1093/rpd/ncq237. Epub 2010 Sep 10.
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Human exposure to high natural background radiation: what can it teach us about radiation risks?
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Room model with three modal distributions of attached 220Rn progeny and dose conversion factor.具有附着的220Rn子体三种模态分布和剂量转换因子的房间模型。
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Microdosimetric calculation of absorption fraction and the resulting dose conversion factor for radon progeny.氡子体吸收分数及由此产生的剂量转换系数的微剂量学计算。
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