Karolinska Institutet, Department of Laboratory Medicine, Division of Clinical Pharmacology L7:05, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
Eur J Clin Pharmacol. 2011 Oct;67(10):1085-9. doi: 10.1007/s00228-011-1057-9. Epub 2011 May 11.
We performed a systematic analysis of which drugs, prescribed, over the counter (OTC), and/or natural remedies, children had used prior to visiting a pediatric emergency room (ER), and to compare this information with the documentation of drug use in the medical records.
A questionnaire study was performed at a pediatric ER in a Swedish university hospital during 3 weeks in April 2008. The questionnaire was validated through an interview with a subgroup of participants. Only drug use associated with the time of that hospital visit was requested. Information was compared with information in medical records related to the same visit.
Two hundred and seventy-four children aged 0-18 (median 2) years were enrolled, representing 28% of the total number of patients visiting the ER within the time frame. Forty% (n = 109) of participants reported use of prescribed drugs, 65% (n = 172) OTC drugs, and 8% (n = 17) natural remedies prior to the ER visit. The most common drugs in the three groups were salbutamol, paracetamol, and omega fatty acids, respectively. In the medical records, no more than 50% of the reported drug intake could be found, representing 74% of prescribed drugs but only 34% of OTC drugs and 27% of natural remedies.
The majority of children had used drugs, both prescribed and OTC, before coming to the ER , but this drug intake, and especially that of nonprescribed drugs, was often not documented in the medical records.
我们对儿童在前往儿科急诊室就诊之前使用的药物进行了系统分析,包括处方药物、非处方药物(OTC)和/或天然药物,并将这些信息与病历中的药物使用记录进行比较。
2008 年 4 月,在瑞典一所大学医院的儿科急诊室进行了一项问卷调查研究。该问卷通过对部分参与者的访谈进行了验证。仅要求报告与该次就诊时间相关的药物使用信息。将所获得的信息与同一就诊相关的病历信息进行比较。
共纳入了 274 名 0-18 岁(中位数为 2 岁)的儿童,占该时间段内就诊于急诊室的总患者数的 28%。40%(n=109)的参与者报告在就诊前使用了处方药物,65%(n=172)使用了 OTC 药物,8%(n=17)使用了天然药物。这三组中最常见的药物分别为沙丁胺醇、对乙酰氨基酚和欧米伽脂肪酸。在病历中,仅发现了报告药物摄入的 50%以下,其中包括 74%的处方药物,但仅包括 34%的 OTC 药物和 27%的天然药物。
大多数儿童在前往急诊室之前都使用过药物,包括处方药物和 OTC 药物,但这些药物的使用情况,尤其是非处方药物的使用情况,在病历中往往没有记录。