Department of Oral and Maxillofacial Surgery and Maxillofacial Prosthetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands.
Head Neck. 2011 Jun;33(6):831-9. doi: 10.1002/hed.21544. Epub 2010 Dec 9.
The purpose of this prospective study was to assess the quality of life (QOL) and oral functioning of patients with oral cancer up to 5 years after prosthodontic rehabilitation with mandibular implant-retained overdentures.
Fifty patients who had received implants during ablative surgery were evaluated by standardized questionnaires before and after oncological and prosthetic treatment.
In 20 of 24 surviving patients, the dentures were functional after 5 years. In these survivors, oral function remained unchanged during this period. In the 6 patients with concurrent comorbidity, global health and QOL had deteriorated, while in the patients without comorbidity, global health and QOL were very high. Five-year survivors had a higher global health and better oral functioning at the 1-year evaluation than nonsurvivors.
Oral function and denture satisfaction were high and did not change over time for survivors. Deterioration in overall global health and QOL was associated with concurrent comorbidity.
本前瞻性研究的目的是评估口腔癌患者在接受下颌种植覆盖义齿修复后 5 年内的生活质量（QOL）和口腔功能。
对 50 名接受过根治性手术的患者进行评估，在肿瘤学和修复治疗前后使用标准化问卷进行评估。
24 名存活患者中有 20 名在 5 年后义齿功能正常。在此期间，这些幸存者的口腔功能保持不变。在 6 名伴有合并症的患者中，整体健康状况和 QOL 恶化，而在无合并症的患者中，整体健康状况和 QOL 非常高。5 年幸存者在 1 年评估时的整体健康状况和口腔功能优于非幸存者。
对于幸存者来说，口腔功能和义齿满意度高且随时间变化不大。整体全球健康状况和 QOL 的恶化与合并症有关。
