Grobe H R, Kunath F, Tramèr M R, Lang B, Meerpohl J J
Deutsches Cochrane Zentrum, Institut für Medizinische Biometrie und Medizinische Informatik, Abt. Med. Biometrie und Statistik, Universitätsklinikum Freiburg, Deutschland.
Anaesthesist. 2011 May;60(5):407-10, 412-3. doi: 10.1007/s00101-011-1895-y.
In the interest of patients evidence-based healthcare should be provided and is increasingly being demanded worldwide. In the daily medical practice however, healthcare based on proven scientific findings has not yet become firmly established. There are several causes for this. Problems occur at the level of knowledge generation, knowledge transfer from research into practice and also at the individual level of the treating healthcare professional. Nowadays, with a rapidly growing amount of knowledge it is almost impossible for the individual to quickly filter out the relevant facts. This article aims to shed light on the various aspects of the process of knowledge transfer from a clinical trial to evidence-based guidelines. It will make the reader aware of potential problems during this process and show some feasible approaches to solving them. Wherever possible, the field of anesthesiology will be used as the reference point. Evidence-based information sources will be presented and advice on how to use them will be given.
为了患者的利益,应提供循证医疗保健,并且在全球范围内对其的需求日益增加。然而,在日常医疗实践中,基于已证实科学发现的医疗保健尚未牢固确立。造成这种情况有几个原因。问题出在知识生成层面、从研究到实践的知识转移层面,以及治疗医疗专业人员的个人层面。如今,随着知识量的迅速增长,个人几乎不可能快速筛选出相关事实。本文旨在阐明从临床试验到循证指南的知识转移过程的各个方面。它将使读者意识到这一过程中的潜在问题,并展示一些解决这些问题的可行方法。只要有可能,将以麻醉学领域作为参考点。将介绍循证信息来源并给出如何使用它们的建议。