[自发性血肿与活化部分凝血活酶时间（aPTT）单独延长]

[Spontaneous hematomas and isolated prolongation of aPTT].

作者信息

Heimgartner B, Oestmann A, Keller P, Rüsges-Wolter I

机构信息

Universitätsklinik für Allgemeine Innere Medizin, Inselspital, Universitätsspital Bern, Freiburgstrase 10, 3010 Bern.

出版信息

Praxis (Bern 1994). 2011 May 11;100(10):603-6. doi: 10.1024/1661-8157/a000532.

DOI:10.1024/1661-8157/a000532

PMID:21563098

Abstract

We report a case of a 64 year old woman with spontaneous hematomas. A prior history of bleeding disorder was not known up to now. The result of investigation of coagulation was an isolated prolonged aPTT that was caused by an inhibitor of factor VIII without underlying disease (idiopathic acquired hemophilia A). Therapy with steroids and cyclophosphamid resulted in partial remission.

摘要

我们报告一例64岁患有自发性血肿的女性病例。截至目前，此前并无出血性疾病史。凝血检查结果显示，活化部分凝血活酶时间（aPTT）单独延长，这是由无基础疾病（特发性获得性血友病A）的VIII因子抑制剂引起的。使用类固醇和环磷酰胺治疗后病情部分缓解。