Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
J Magn Reson Imaging. 2011 Mar;33(3):598-602. doi: 10.1002/jmri.22503.
To provide the first description of a pattern of iron deposition surrounding the hepatic veins in patients with alcoholic cirrhosis and postulate the reason for these findings.
Two institutions' teaching files were searched for abdominal MRI studies between January 2003 and April 2009 which showed iron deposition within the liver surrounding the hepatic veins. MRI exams were reviewed by two radiologists for iron deposition and signs of portal hypertension. Liver explant pathology reports were also reviewed.
Four patients with alcoholic cirrhosis demonstrated perihepatic vein low signal intensity on T1 gradient echo images correlating with iron overload confirmed at histopathologic evaluation of explanted livers.
This is the first described uncommon distribution of iron deposition surrounding the hepatic veins. This pattern is well seen on in-phase T1 gradient echo sequences because of the T2* effects in this sequence.
描述肝硬化患者肝静脉周围铁沉积的模式，并推测这些发现的原因。
检索 2003 年 1 月至 2009 年 4 月期间两家机构的教学档案，寻找显示肝静脉周围肝脏内铁沉积的腹部 MRI 研究。由两名放射科医生对 MRI 检查进行铁沉积和门脉高压征象的评估。还回顾了肝活检标本的病理学报告。
4 例酒精性肝硬化患者的 T1 梯度回波图像显示肝周静脉低信号强度，与肝移植标本的组织病理学铁过载评估结果相符。
这是首次描述肝静脉周围铁沉积的这种罕见分布模式。由于该序列的 T2*效应，在同相位 T1 梯度回波序列中可以很好地观察到这种模式。
