Rahman Rubina, Briffa Benedict Vella, Gupta Abha, Chinn David J
Calderdale Royal Hospital, Halifax, United Kingdom.
Ophthalmic Surg Lasers Imaging. 2011 May-Jun;42(3):229-33. doi: 10.3928/15428877-20110420-02.
To determine posterior capsule opacification (PCO) rate and identify contributory factors in a series of patients undergoing combined 23-gauge transconjunctival phacovitrectomy.
Retrospective data on 221 consecutive patients operated on by a single senior surgeon using a standard technique were collected and subjected to univariate analysis with chi-square tests and multivariate analysis with logistic regression.
PCO developed in 46 of 221 cases (20.8%). Major risk factors were: rhegmatogenous retinal detachment (relative risk = 3.3, P = .002), axial length greater than 24.5 mm (relative risk = 2.0, P = .093), intraoperative/postoperative complications (relative risk = 3.3, P = .04), C2F6 tamponade (versus SF6/air) (relative risk = 2.8, P = .01), and postoperative posturing (relative risk = 4.1, P < .001). Multiple logistic regression analysis showed the latter two to be most important.
PCO rate following 23-gauge phacovitrectomy is lower than most rates reported for 20-gauge phacovitrectomy. Using shorter-acting gas tamponade and avoiding postoperative posturing may help lower PCO rates.
确定接受23G经结膜无缝线白内障玻璃体切除术患者的后囊膜混浊（PCO）发生率，并识别相关因素。
收集由同一位资深外科医生采用标准技术连续手术的221例患者的回顾性数据，采用卡方检验进行单因素分析，并采用逻辑回归进行多因素分析。
221例患者中有46例（20.8%）发生PCO。主要危险因素为：孔源性视网膜脱离（相对风险=3.3，P=0.002）、眼轴长度大于24.5mm（相对风险=2.0，P=0.093）、术中/术后并发症（相对风险=3.3，P=0.04）、C2F6气体填充（对比SF6/空气）（相对风险=2.8，P=0.01）以及术后体位（相对风险=4.1，P<0.001）。多因素逻辑回归分析显示后两者最为重要。
23G白内障玻璃体切除术后的PCO发生率低于多数报道的20G白内障玻璃体切除术的发生率。使用短效气体填充并避免术后体位可能有助于降低PCO发生率。
