El Choueiry E, Cuzon G, Dugelay F, Chevret L, Durand P, Bergounioux J
Service de réanimation pédiatrique polyvalente, hôpital de Bicêtre, 63, avenue Gabriel-Péri, 94270 Le-Kremlin-Bicêtre, France.
Arch Pediatr. 2011 Jul;18(7):767-71. doi: 10.1016/j.arcped.2011.04.004. Epub 2011 May 11.
Acute necrotizing pneumonia due to Panton-Valentine secreting Staphylococcus aureus was identified as a clinical entity by Gilet et al., in 2002. This severe acute necrotizing pneumonia occurring in previously healthy children and adolescents can lead to a rapid fatal outcome even if quickly diagnosed and treated. We report the case of a healthy 10-year-old girl presenting with hemorrhagic necrotizing pneumonia and septic shock. Bacteriological cultures yielded methicillin-susceptible Staphylococcus aureus. The course of the disease was characterized by recurrent uncontrolled hemoptysia leading to refractory hypoxemia. The details of the hospital stay are presented. We discuss the clinical features of the disease and describe recent epidemiologic data and Panton-Valentine toxin research results as well as primary hospital care and treatment.
2002年，吉莱特等人将由分泌杀白细胞素的金黄色葡萄球菌引起的急性坏死性肺炎确定为一种临床实体。这种发生在原本健康的儿童和青少年身上的严重急性坏死性肺炎，即使能迅速诊断和治疗，也可能导致迅速的致命后果。我们报告了一例健康的10岁女孩，她患有出血性坏死性肺炎和感染性休克。细菌培养结果显示为对甲氧西林敏感的金黄色葡萄球菌。该疾病的病程特点是反复出现无法控制的咯血，导致难治性低氧血症。本文介绍了住院期间的详细情况。我们讨论了该疾病的临床特征，并描述了近期的流行病学数据、杀白细胞素研究结果以及医院的初步护理和治疗情况。
